This paper applies RFID technology to the enterprise’s supply chain system, combined with supply chain management, through RFID to achieve the automated collection of logistics information to improve the operational efficiency and management service level. Relying on the case enterprise through continuous recording and tracking for the application of this technology in a supply chain system to carry out further research through the combination of theory and data, showing more advantages of an intelligent logistics supply chain. The results show that compared with the original system, the intelligent logistics supply chain has better efficiency and accuracy, and label identification has reached 100%. After the implementation of the RFID intelligent supply chain, JZ company’s purchasing, logistics, and production costs showed a downward trend, while profitability and operating capacity showed an upward trend.