“…However, the use of the allograft should be cautious, as transmission of pathogens may occur if safety measures are not undertaken (Frost, Fonseca, & Burkes Jr., 1982). Regarding the use of heterologous bone, some studies show negative results (Ledford, Nunley 2nd, Viens, & Lark, 2013;Levai, Bringer, Descamps, & Boisgard, 2003) and other studies show positive results (Astore, Ricci, Ursino, & Spotorno, 2005;Athanasiou et al, 2010;Calasans-Maia et al, 2014;Ramirez-Fernandez et al, 2013).…”