Retroperitoneal germinomas (seminomas) without evidence of testicular involvement

Abell, Murray R.; Fayos, Juan V.; Lampé, I

doi:10.1002/1097-0142(196503)18:3<273::aid-cncr2820180304>3.0.co;2-3

Cited by 110 publications

(19 citation statements)

References 16 publications

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“…Because bilaterally the testes were normal on ultrasound examination and there was no evidence to indicate the disease outside of the prostate on CT and MRI scans, we judged the present case as a primary seminoma of the prostate. However, it is still possible that a seminoma in the testes and/or another place vanished after metastasis to the prostate 2,4,6,8 . Therefore, a careful follow‐up examination of the entire body, including the lungs, retroperitoneal lymph node, and both testes, is necessary.…”

Section: Discussionmentioning

confidence: 99%

Primary seminoma of the prostate

Hashimoto

Ohori²,

Sakamoto³

et al. 2009

Int J of Urology

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Abstract:A 54-year-old gentleman was suspected of having sarcoma of the prostate because of his low serum prostatespecific antigen level (1.9 ng/mL) and an enlarged heterogeneous mass on computed tomography and magnetic resonance imaging scans. Pathological examination of the prostate needle biopsy indicated seminoma, which was confirmed with immunohistochemical staining. There was no evidence of disease in other areas on physical examination or on radiographic tests. Therefore, we diagnosed the case as a primary seminoma of the prostate, which was consequently treated with a total of three courses of bleomycin, etoposide and cisplatin chemotherapy. Complete response was obtained on computed tomography, magnetic resonance imaging and prostate needle re-biopsy. To our knowledge, there have only been five cases of primary seminoma of the prostate reported.

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Section: Discussionmentioning

confidence: 99%

Primary seminoma of the prostate

Hashimoto

Ohori²,

Sakamoto³

et al. 2009

Int J of Urology

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“…These studies showed favourable outcomes both for short and long follow-up periods with combined modality treatment approach and revealing the higher frequency of metastatic retroperitoneal tumours from primary unevolved testicular tumour [5,[18][19][20][21][22][23] (Table 1). …”

Section: Discussionmentioning

confidence: 99%

A Case Report of Retroperitoneal Seminoma and Literature Review

Chiumento¹

2013

J Nucl Med Radiat Ther

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Aims and background: Extra-gonadal germ cell tumours (EGCT) are rare tumors, which usually occur in the mediastinum or retroperitoneum; in particular, primary retroperitoneal seminomas account for approximately 2% of all seminomas. We report the case of a 34-year-old male with a locally advanced retroperitonal seminoma. Methods:The patient underwent debulking surgery followed by cisplatin-based chemotherapy and radiotherapy. Results: No evidence of recurrence was detected during a 30 months follow-up. Although retroperitoneal seminoma is rare, this entity should be considered in the differential diagnosis of a male patient presenting with a mass in the retroperitoneum. Conclusions:Our case, according to data reported in literature, confirms the curability of retroperitoneal seminoma even in presence of bulky disease, and it represents an example of revised treatment procedure due to patient's particular condition.

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“…Patients with retroperitoneal germ cell tumors usually present late, after their tumors have reached large dimensions. Presenting symptoms and signs include a palpable mass, with or without pain, weight loss, constipation, hip and back pain, dyspnea, leg edema, fever, varicocele, and urinary retention [3, 4]. …”

Section: Discussionmentioning

confidence: 99%

Burned-Out Testicular Tumor: A Case Report

Balalaa

Hassen³

2011

Case Rep Oncol

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Germ cell tumors constitute the majority of all testicular tumors, which are relatively rare overall and are mainly encountered in young adults and teenagers. The term ‘burned-out’ germ cell tumor refers to the presence of a metastatic germ cell tumor with histological regression of the primary testicular lesion. Clinical examination of the testes and scrotal sonography is pivotal in the initial diagnosis of such neoplasms. We present a case of a 31-year-old male with a retroperitoneal mass and no palpable lesion on testicular examination.

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Retroperitoneal germinomas (seminomas) without evidence of testicular involvement

Cited by 110 publications

References 16 publications

Primary seminoma of the prostate

Primary seminoma of the prostate

A Case Report of Retroperitoneal Seminoma and Literature Review

Burned-Out Testicular Tumor: A Case Report

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