Retroperitoneal sarcoma-like malakoplakia

Dias, Paulo Henrique Goulart Fernandes; Slongo, Luiz Edison; Romero, Frederico R.; Paques, Guilherme R.; Gomes, Regina Paula X.; Rocha, Luiz Carlos de Almeida

doi:10.1590/s0104-42302011000600005

Cited by 5 publications

(2 citation statements)

References 8 publications

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“…Ascorbic acid can enhance lysozyme damage caused by immune deficiency. Therefore, the combination of antibiotics, vitamin C, and cholinergic drugs may have a certain effect ( 41 – 44 ).…”

Section: Discussionmentioning

confidence: 99%

Case report: A rare case of malacoplakia resembling a malignant tumor of the cervix: a case report and review of the literature

Li,

Mi,

Wang

et al. 2024

Front. Med.

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Malacoplakia is a rare chronic granulomatous disease that mostly affects the gastrointestinal tract and urinary tract of immunocompromised patients; malacoplakia rarely effects the female reproductive tract. Here, we report a 56-year-old patient who underwent thymectomy for thymoma and myasthenia gravis prior to developing cervical and vaginal malacoplakia. The patient presented with recurrent vaginal bleeding. We discovered that there were alterations in the cervical cauliflower pattern during colposcopy, which is suggestive of cervical cancer. Pathological examination of the lesion tissue showed that a large number of macrophages aggregated, and M-G bodies with concentric circles and refractive properties were observed between cells. Immunostaining for CD68 and CD163 was positive, and special staining for D-PAS and PAS was positive. The discovery of Escherichia coli in bacterial culture can aid in the diagnosis of malacoplakia. Following surgery, we performed vaginal lavage with antibiotics in addition to resection of local cervical and vaginal lesions. This study provides a fresh perspective on the management of genital malacoplakia.

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“…Ascorbic acid can enhance lysozyme damage caused by immune deficiency. Therefore, the combination of antibiotics, vitamin C, and cholinergic drugs may have a certain effect ( 41 – 44 ).…”

Section: Discussionmentioning

confidence: 99%

Case report: A rare case of malacoplakia resembling a malignant tumor of the cervix: a case report and review of the literature

Li,

Mi,

Wang

et al. 2024

Front. Med.

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“…In this case, malakoplakia resulted from bacterial infection in the pelvis that was first diagnosed as TOA and immunosuppression due to oral steroids and diabetes mellitus. Malakoplakia can affect various organs including the skin, lungs, and bones [ 4 , 5 ]. A literature review showed several reports of malakoplakia occurring in female pelvic organs involving the ovary and fallopian tube [ 6 , 7 ]; however, this is a very rare case of pelvic malakoplakia in the uterus without adnexa due to previous surgery and involving the full depth of the uterus, thus mimicking endometrial cancer as detected in imaging studies.…”

Section: Discussionmentioning

confidence: 99%

Pelvic malakoplakia presenting as endometrial cancer: a case report

et al. 2020

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Malakoplakia is a rare granulomatous, inflammatory disease generally manifesting as ulcers of the urogenital tract, especially in the bladder, but it can occur in any part of the body. Because of its varied clinical presentations, malakoplakia is considered for differential diagnosis upon suspicion. The final diagnosis is confirmed by the presence of Michaelis-Gutmann bodies. We report a case of pelvic malakoplakia accompanied by left lower quadrant pain that was misdiagnosed as endometrial cancer with pelvic mass based on imaging studies. The patient underwent dilatation and curettage, and the pathology report revealed no malignancy. Because of persistent pain and septic shock, she underwent a debulking operation to remove the mass. Histopathologic examination revealed malakoplakia. For postoperative management, she received broad-spectrum antibiotics, but abdominal pelvic computerized tomography performed on postoperative day 9 revealed pelvic mass recurrence. To the best of our knowledge, this is the only rare case report of pelvic malakoplakia mimicking endometrial cancer.

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Outgrowing skin involvement in malakoplakia after kidney transplantation: A case report

Lee

Park

et al. 2022

Transplantation Proceedings

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Retroperitoneal sarcoma-like malakoplakia

Cited by 5 publications

References 8 publications

Case report: A rare case of malacoplakia resembling a malignant tumor of the cervix: a case report and review of the literature

Case report: A rare case of malacoplakia resembling a malignant tumor of the cervix: a case report and review of the literature

Pelvic malakoplakia presenting as endometrial cancer: a case report

Outgrowing skin involvement in malakoplakia after kidney transplantation: A case report

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