2012
DOI: 10.1007/s13193-012-0152-4
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Retroperitoneal Sarcomas- A Challenging Problem

Abstract: Retroperitoneal sarcomas are relatively rare tumours and usually present in a locally advanced stage. Liposarcoma is the most common histopathology. If operable, surgery is the treatment of choice. The role of adjuvant chemotherapy or radiotherapy is not yet defined. Advanced cases are treated by chemotherapy. The prognosis is poor in patients with positive resection margins, high-grade tumours and recurrent tumours.

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Cited by 10 publications
(6 citation statements)
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“…Studies in extremity sarcomas have demonstrated improved local control rates when surgery was combined with radiotherapy. Globally, the sensitivity of sarcomas to irradiation is low [ 14 ]. However, there is no consensus regarding use of neoadjuvant or adjuvant chemotherapy.…”
Section: Discussionmentioning
confidence: 99%
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“…Studies in extremity sarcomas have demonstrated improved local control rates when surgery was combined with radiotherapy. Globally, the sensitivity of sarcomas to irradiation is low [ 14 ]. However, there is no consensus regarding use of neoadjuvant or adjuvant chemotherapy.…”
Section: Discussionmentioning
confidence: 99%
“…The disadvantages are that a tumour may not respond to chemotherapy and a potentially resectable tumour may become inoperable. Chemotherapy may also worsen the performance status of the patient [ 14 ]. Several studies, most of them non-randomized have not shown any consistent benefit withNACT.…”
Section: Discussionmentioning
confidence: 99%
“…Although our patient had sarcoma, given the rapidly progressive nature of disease after surgery, flap was applied and followed by post-operative protocol for viability. It's been reported that patients with poorly differentiated sarcoma, had an increased chance of survival [9]. However, to confirm radiological and clinical findings, cytogenetics and chemotherapy was started after 2 weeks of the operation, the patient improved, and flap continued to heal without signs of congestion (Figure 4).…”
Section: Discussionmentioning
confidence: 78%
“…cT scan helps to delineate size and extent as well as relationship with nearby vessels, organs, and skeletal structures. it also detects metastasis and gives crucial information regarding plan for surgical resection of tumor (Kumar V et al, 2012). liposarcomas are classified based on histology, morphology, and cytogenetic differences.…”
Section: Discussionmentioning
confidence: 99%