Retrospective study assessing efficacy and safety of left atrial appendage occlusion

Abstract

Slovakia. To evaluate procedural effi cacy and safety. BACKGROUND: Atrial fi brillation increases the risk of stroke. While anticoagulation therapy can reduce the risk of stroke, it is associated with bleeding risk and often unsatisfactory prescribed. Most thrombi form in the left atrium appendage, hence left atrium appendage occlusion may be a suitable therapeutic alternative for these patients. METHODS: This is an observational, retrospective, single-centre, case-series study including 30 patients with atrial fi brillation at a high risk of stroke, undergoing left atrial appendage occlusion from June 2015 to December 2018. RESULTS: The left atrial appendage was successfully closed in 29 (96.7 %) patients. Three months after the procedure, 4 patients had small leaks (< 2 mm). No complications were reported so far. Prior to the procedure, patients mostly received low molecular weight heparin (53.3 %). Three months after the procedure, patients mostly received acetylsalicylic acid (60.7 %) and clopidogrel (32.1 %). CONCLUSION: Left atrial appendage occlusion was shown to be an effective and safe alternative to anticoagulation therapy in patients with atrial fi brillation, at a high risk of stroke and bleeding. The procedure is safe, when performed carefully even by less experienced cardiologists (Tab. 6, Fig. 4, Ref.

Katetrizačný uzáver uška ľavej predsiene, včasné a neskoré komplikácie / Left atrial appendage occlusion, early and late complications

“…Uzáver sa zavádzal pod skiaskopickou a echokardiografickou kontrolou v celkovej anestézii u 48 pacientov, u ktorých bola zavedená ezofágová sonda pre účely echokardiografie a v lokálnej anestézii u jednej pacientky, kedy sa pre striktúru pažeráka použila intrakardiálna echokardiografia. Po získaní prvých skúseností sme si vypracovali vlastný protokol zavádzania uzáveru (11). Set na transseptálnu punkciu bol zavedený cez v. femoralis l. dx.…”