Retrospective study on factors affecting the prognosis in oral cancer patients who underwent surgical treatment only

Abstract

BackgroundThis study was performed to evaluate their 5-year survival rates and identify the factors affecting the prognosis of oral cancer patients who had undergone surgical treatment only.MethodsAmong 130 patients who were diagnosed with malignant tumor of oral, maxillofacial, and surgical treated in the Department of Oral and Maxillofacial Surgery at Chonnam National University Hospital within a period from January 2000 to December 2010, for 11 years, 84 patients were investigated who were followed up for more than 5 years after radical surgery; oral cancer is primary and received only surgical treatment. The survival rate according to gender, age, type and site of cancer, TNM stage, cervical lymph node metastasis and its stage, recurrence or metastasis, time of recurrence and metastasis, and differentiation were investigated and analyzed.ResultsOverall, 5-year survival rate in patients who received only surgical treatment was 81.2 %, and disease-specific 5-year survival rate was 83.1 %. The disease-specific 5-year survival rate based on TNM stage, metastasis of cervical lymph node, N stage, and presence of recurrence/metastasis was a significant difference (p < 0.05). The disease-specific 5-year survival rate based on sex, age, type of tumor, primary site, and differentiation was not a significant difference (p > 0.05).ConclusionsThese results suggest that good survival rate can be obtained with surgical treatment only, and stage of oral cancer, cervical lymph node metastasis and stage, recurrence or metastasis, time of recurrence, and metastasis have a significant effect on survival rate in oral cancer patients.

Overall and disease-specific survival outcomes following primary surgery for oral squamous cell carcinoma: analysis of consecutive 67 patients

“…Two factors that were related to OS and DSS were pTNM stage and presence of neck node metastasis. Studies have shown that patients with advanced-stage disease have lower survival3. In fact, a recent study states that the most important clinical predictor of survival remains TNM stage at the time of diagnosis8.…”

“…Oral squamous cell carcinoma (OSCC) is a common malignancy worldwide, with regional variations in incidence and mortality123. The most common risk factors associated with OSCC are tobacco and alcohol abuse4; however, the incidence in younger than 40 years without tobacco and alcohol abuse has increased5.…”

Reconstruction of partial maxillectomy defect with a buccal fat pad flap and application of 4-hexylresorcinol: a case report

“…Low-grade MEC is surgically excised in a single piece along with the involved underlying mucosa and bone for an adequate tumor-free margin5. High-grade MEC has local infiltration and regional lymph node metastasis1415, requiring wider surgical resection with postoperative radiotherapy or chemotherapy116. Lymph node metastasis can occur in low-grade MEC1.…”

The establishment of the Asia‐Pacific Oral Cancer Network—Inaugural stakeholders' Meeting

“…These challenges include the lack of systematic documentation of the disease (<2% of Asian's population is covered by population‐based registries (Ferlay et al, 2015), high use of smoked and smokeless tobacco (Ansara et al, 2013; Eriksen, Mackay, Schluger, & Islami, 2015) and limited access to diagnosis and treatment to name a few. Diagnosis at an early disease stage improves oral cancer survival, thus there is a critical need for effective strategies in promoting early detection (Ghani et al, 2019; Kim et al, 2016).…”