Reviewing Microbial Behaviors in Ecosystems Leading to a Natural Quorum Quenching Occurrence

Sierra-Zapata, Laura; Romero-Tabarez, Magally; Álvarez, Javier Correa; Escobar, Valeska Villegas

doi:10.1590/1678-4324-2017160295

Cited by 3 publications

(1 citation statement)

References 53 publications

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“…Bacteria, Eukaryota, and Archaea can produce and respond to chemical signals called autoinducers (AIs) that are extracellular small diffusible molecules [ 39 ]. These compounds have low molecular mass (100–300 Daltons, up to C20), generally with a low boiling point and high vapor pressure [ 40 ].…”

Section: Obtaining Fungal Secondary Metabolites and Structural Charac...mentioning

confidence: 99%

Overview of Bioactive Fungal Secondary Metabolites: Cytotoxic and Antimicrobial Compounds

et al. 2022

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Microorganisms are known as important sources of natural compounds that have been studied and applied for different purposes in distinct areas. Specifically, in the pharmaceutical area, fungi have been explored mainly as sources of antibiotics, antiviral, anti-inflammatory, enzyme inhibitors, hypercholesteremic, antineoplastic/antitumor, immunomodulators, and immunosuppressants agents. However, historically, the high demand for new antimicrobial and antitumor agents has not been sufficiently attended by the drug discovery process, highlighting the relevance of intensifying studies to reach sustainable employment of the huge world biodiversity, including the microorganisms. Therefore, this review describes the main approaches and tools applied in the search for bioactive secondary metabolites, as well as presents several examples of compounds produced by different fungi species with proven pharmacological effects and additional examples of fungal cytotoxic and antimicrobial molecules. The review does not cover all fungal secondary metabolites already described; however, it presents some reports that can be useful at any phase of the drug discovery process, mainly for pharmaceutical applications.

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Section: Obtaining Fungal Secondary Metabolites and Structural Charac...mentioning

confidence: 99%

Overview of Bioactive Fungal Secondary Metabolites: Cytotoxic and Antimicrobial Compounds

et al. 2022

View full text Add to dashboard Cite

show abstract

Nano-biofertilizers: Harnessing Dual Benefits of Nano-nutrient and Bio-fertilizers for Enhanced Nutrient Use Efficiency and Sustainable Productivity

Kalia

Kaur

2019

Nanoscience for Sustainable Agriculture

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Endophytes as emphatic communication barriers of quorum sensing in Gram-positive and Gram-negative bacteria—a review

Kumar

Singh

Mishra

2019

Environmental Sustainability

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Reviewing Microbial Behaviors in Ecosystems Leading to a Natural Quorum Quenching Occurrence

Cited by 3 publications

References 53 publications

Overview of Bioactive Fungal Secondary Metabolites: Cytotoxic and Antimicrobial Compounds

Overview of Bioactive Fungal Secondary Metabolites: Cytotoxic and Antimicrobial Compounds

Nano-biofertilizers: Harnessing Dual Benefits of Nano-nutrient and Bio-fertilizers for Enhanced Nutrient Use Efficiency and Sustainable Productivity

Endophytes as emphatic communication barriers of quorum sensing in Gram-positive and Gram-negative bacteria—a review

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