“…Many materials, such as tricalcium phosphate 9,49,51,59) , polylactic acid polymer 14) , collagen 7,10,44,55) , demineralized bone matrix 14,21,44) , hydroxyapatite 17,24,29,36) , gelatin 18) , fibrin sealant 22) , polylactic-polyglycolic polymer 4,26,31,44,58) , and composites of these materials 19,37,40,60) have been used and evaluated as a BMP carrier for healing of bone defects. Some of the BMP carrier requirements have been satisfied by these materials, but a rapidly resorbable carrier that has the desirable mechanical and plastic properties has yet to be developed.…”