1998
DOI: 10.1006/excr.1997.3835
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Ribosomal DNA Replication in the Fission Yeast,Schizosaccharomyces pombe

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Cited by 73 publications
(82 citation statements)
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“…Previous work with S. cerevisiae and S. pombe has shown that Slx1-Slx4 complex is a structure-specific DNA endonuclease that is essential for maintenance of the rDNA array in the absence of Sgs1/Rqh1 DNA helicase (Kaliraman and Brill, 2002;Fricke and Brill, 2003;Coulon et al, 2004). The studies in S. cerevisiae further (Sanchez et al, 1998) and diagram of the migration pattern of replication intermediate that can be detected by 2D-gel electrophoresis. The ARS3001 box indicates the origin region, and the RFB box indicates a pause site (Sanchez et al, 1998).…”
mentioning
confidence: 77%
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“…Previous work with S. cerevisiae and S. pombe has shown that Slx1-Slx4 complex is a structure-specific DNA endonuclease that is essential for maintenance of the rDNA array in the absence of Sgs1/Rqh1 DNA helicase (Kaliraman and Brill, 2002;Fricke and Brill, 2003;Coulon et al, 2004). The studies in S. cerevisiae further (Sanchez et al, 1998) and diagram of the migration pattern of replication intermediate that can be detected by 2D-gel electrophoresis. The ARS3001 box indicates the origin region, and the RFB box indicates a pause site (Sanchez et al, 1998).…”
mentioning
confidence: 77%
“…Y structures arise from moving replication forks within the BamHI fragment (Figure 5A). Pausing of replication forks at specific sites causes the accumulation of identical Y structures visible as distinct spots on the Y arc (Sanchez et al, 1998). X-shaped DNA structures are thought to arise from converged forks or recombination associated with DNA replication ( Figure 5A).…”
Section: Expression Of Slx1-r34a Dominant Negative Allele In a Rqh1⌬ mentioning
confidence: 99%
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“…However, similarities between the two yeast models have been established. In particular, S. pombe has a pausing site at the 3Ј end of the 35S gene acting like the RFB (Sanchez et al, 1998). This pausing site enforces unidirectional replication of rDNA in S. pombe.…”
Section: Slx1-slx4 Endonucleasementioning
confidence: 99%