Rice Bran, an Alternative Nitrogen Source for Acetobacter xylinum Bacterial Cellulose Synthesis

Narh, Christopher; Frimpong, Charles; Mensah, Alfred; Wei, Qufu

doi:10.15376/biores.13.2.4346-4363

Cited by 16 publications

(9 citation statements)

References 49 publications

(63 reference statements)

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“…Regarding the raw materials for producing BC, both the need to reduce costs and the need to provide more sustainable productions, encouraged the use of vegetable waste feedstocks containing suitable carbon sources (Kuo et al, 2010; Cheng et al, 2017; Costa et al, 2017). Promising results were provided from lignocellulosic materials such as wheat straw, sugarcane bagasse, rice straw, hydrolysate fiber sludge, and corn steep liquor (Hwang et al, 1999; da Silva Filho et al, 2006; Cavka et al, 2013; Narh et al, 2018). Carbon sources mainly contained in these products are glucose, sucrose, and polyols as mannitol and xylitol, that are also naturally found in fruits, other vegetables, and also produced by bacteria and yeasts (Song and Vieille, 2009).…”

Section: Introductionmentioning

confidence: 99%

Exploring K2G30 Genome: A High Bacterial Cellulose Producing Strain in Glucose and Mannitol Based Media

et al. 2019

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Demands for renewable and sustainable biopolymers have rapidly increased in the last decades along with environmental issues. In this context, bacterial cellulose, as renewable and biodegradable biopolymer has received considerable attention. Particularly, acetic acid bacteria of the Komagataeibacter xylinus species can produce bacterial cellulose from several carbon sources. To fully exploit metabolic potential of cellulose producing acetic acid bacteria, an understanding of the ability of producing bacterial cellulose from different carbon sources and the characterization of the genes involved in the synthesis is required. Here, K2G30 (UMCC 2756) was studied with respect to bacterial cellulose production in mannitol, xylitol and glucose media. Moreover, the draft genome sequence with a focus on cellulose related genes was produced. A pH reduction and gluconic acid formation was observed in glucose medium which allowed to produce 6.14 ± 0.02 g/L of bacterial cellulose; the highest bacterial cellulose production obtained was in 1.5% (w/v) mannitol medium (8.77 ± 0.04 g/L), while xylitol provided the lowest (1.35 ± 0.05 g/L) yield. Genomic analysis of K2G30 revealed a peculiar gene sets of cellulose synthase; three bcs operons and a fourth copy of bcsAB gene, that encodes the catalytic core of cellulose synthase. These features can explain the high amount of bacterial cellulose produced by K2G30 strain. Results of this study provide valuable information to industrially exploit acetic acid bacteria in producing bacterial cellulose from different carbon sources including vegetable waste feedstocks containing mannitol.

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Section: Introductionmentioning

confidence: 99%

Exploring K2G30 Genome: A High Bacterial Cellulose Producing Strain in Glucose and Mannitol Based Media

et al. 2019

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“…The clean BC membranes were prepared as reported elsewhere [41] due to the ease of preparation, prolific yield and enhanced crystallinity. This synthesis method had minor modifications compared to the established methods [42,43].…”

Section: Preparation Of Clean Bcmentioning

confidence: 99%

Bioactive Icariin/β-CD-IC/Bacterial Cellulose with Enhanced Biomedical Potential

et al. 2021

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A “super” bioactive antibacterial hydrogel, Icariin-β-CD-inclusion complex/Bacterial cellulose and an equally capable counterpart Icariin-Bacterial cellulose (ICBC) were successfully produced with excellent antioxidant properties. The highly porous hydrogels demonstrated very high fluid/liquid absorption capability and were functionally active as Fourier Transform Infrared Spectrometer (FTIR) test confirmed the existence of abundant hydroxyls (-OH stretching), carboxylic acids (-CH2/C-O stretching), Alkyne/nitrile (C≡C/C≡N stretching with triple bonds) and phenol (C-H/N-O symmetric stretching) functional groups. Scanning electron microscope (SEM) and X-ray diffraction (XRD) tests confirmed a successful β-CD-inclusion complexation with Icariin with a great potential for sustained and controlled drug release. In vitro drug release test results indicated a systemic and controlled release of the drug (Icariin) from the internal cavities of the β-CD inclusion complex incorporated inside the BC matrix with high Icariin (drug) release rates. Impressive inactivation rates against Gram-negative bacteria Escherichia coli ATCC 8099 and gram-positive bacteria Staphylococcus aureus ATCC 6538; >99.19% and >98.89% respectively were recorded, as the materials proved to be non-toxic on L929 cells in the in vitro cytotoxicity test results. The materials with promising versatile multipurpose administration of Icariin for wound dressing (as wound dressers), can also be executed as implants for tissue regeneration, as well as face-mask for cosmetic purposes.

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“…Normally, carbon sources are from glucose but can also be from other carbon sources such as sucrose, fructose, mannitol, and molasses [75,[110][111][112]. Over time, fruit juices and other sources like 5-or 6-carbon monosaccharides, oligosaccharides, glycerol, starch, alcohol and organic acids have successfully been explored for BC growth [113][114][115]. With an increase in initial glucose concentration, the yield of cellulose decreased compared to the glucose absorbed, and gluconic acid accumulated at a high initial glucose concentration [75].…”

Section: Bacteria Bacteria Strains and Growth Factors (Biosynthetic P...mentioning

confidence: 99%

Membrane Technological Pathways and Inherent Structure of Bacterial Cellulose Composites for Drug Delivery

et al. 2021

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This report summarizes efforts undertaken in the area of drug delivery, with a look at further efforts made in the area of bacterial cellulose (BC) biomedical applications in general. There are many current methodologies (past and present) for the creation of BC membrane composites custom-engineered with drug delivery functionality, with brief consideration for very close applications within the broader category of biomedicine. The most emphasis was placed on the crucial aspects that open the door to the possibility of drug delivery or the potential for use as drug carriers. Additionally, consideration has been given to laboratory explorations as well as already established BC-drug delivery systems (DDS) that are either on the market commercially or have been patented in anticipation of future commercialization. The cellulose producing strains, current synthesis and growth pathways, critical aspects and intrinsic morphological features of BC were given maximum consideration, among other crucial aspects of BC DDS.

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Rice Bran, an Alternative Nitrogen Source for Acetobacter xylinum Bacterial Cellulose Synthesis

Cited by 16 publications

References 49 publications

Exploring K2G30 Genome: A High Bacterial Cellulose Producing Strain in Glucose and Mannitol Based Media

Exploring K2G30 Genome: A High Bacterial Cellulose Producing Strain in Glucose and Mannitol Based Media

Bioactive Icariin/β-CD-IC/Bacterial Cellulose with Enhanced Biomedical Potential

Membrane Technological Pathways and Inherent Structure of Bacterial Cellulose Composites for Drug Delivery

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