Ridge augmentation and maxillary sinus grafting with a biphasic calcium phosphate: histologic and histomorphometric observations

Abstract

Data from the present study demonstrated osteoconductivity scores for the BCP material (HA/TCP 60/40) in patients resembling those previously shown for grafting materials of xenogenic and alloplastic origin.

Histological Evaluation of Bone Regeneration Means Freeze Dried Bone Allograft (FDBA) in Post Exodontia Sockets

“…These finding differ from what has been presented as ideal bone regeneration processes, where according to advancement of osteogenesis (in bone regeneration induced by biomaterials), the matrix of fibrillar tissue regresses; formation of bone type I is completed by the third or fourth week, and begins the phase of progressive substitution toward type II bone, where osteoclasts and osteoblasts appear (Anitua & Andia, 2000). At the same time, it also differs with the results presented by other research (Galindo-Moreno et al; Suba et al;Friedmann et al;Gotz et al, 2008;Lee et al, 2008;Norton et al, 2003, who have found that bone genesis produces starting with osteoblasts.…”

“…The use of biomaterials has been evaluated in various regenerative techniques (Friedmann et al;Feuille et al, 2003;Herold et al, 2002;Rosen & Reynolds, 2002;DaneshMeyer et al, 2001;Laurell et al, 1998), with limited research on the use of FDBA in post extraction alveolar ridges.…”

“…Histological studies in humans focus mainly on maxillary sinus lift (Choukroun et al, 2006;Cammack et al, 2005;Yukna & Vastardis, 2005;Kassolis & Reynolds, 2005;Lasella et al, 2003;Markopoulou et al, 2003), lateral or vertical increase of the alveolar ridge and bone regeneration by resection of residual cysts (Friedmann et al, 2009;Galindo-Moreno et al, 2008;Schwartz et al, 2007;Suga et al, 2006;Zerbo et al, 2001).…”

Randomized controlled trial on lateral augmentation using two collagen membranes: morphometric results on mineralized tissue compound

“…Therefore, measurements across alveolar crest perpendicular to the most coronal bony margin performed in this study can be considered standardized. In a previous publication our group demonstrated the degree of mineralization in newly formed tissues exceeding 40% in the area grafted laterally with BCP (Friedmann, et al, 2009). Since in this study biopsies for the histomorphometric analysis were harvested during re-entry surgeries from sites augmented in the present study, histologic outcome indicates an effective denudation of bony crest (Friedmann et al, 2009).…”

“…In a previous publication our group demonstrated the degree of mineralization in newly formed tissues exceeding 40% in the area grafted laterally with BCP (Friedmann, et al, 2009). Since in this study biopsies for the histomorphometric analysis were harvested during re-entry surgeries from sites augmented in the present study, histologic outcome indicates an effective denudation of bony crest (Friedmann et al, 2009). Taking these observations into account and furthermore by removing all non-mineralized tissue from underneath the flap prior to impression we payed maximum attention to establish accuracy of the impressions.…”