2005
DOI: 10.1152/ajpheart.00551.2004
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Right atrial dimension-pressure relation during volume expansion is unaltered by pregnancy in the rat

Abstract: Blood volume expands significantly during pregnancy, but afferent signals from cardiac receptors are reduced. In addition, during exogenous volume expansion, right atrial pressure (RAP) increases more for equivalent volumes in pregnant animals, implying reduced atrial compliance. To examine possible gestational alterations in atrial dimension during volume expansion, we compared the effects of volume expansion on RAP and right atrial dimension (RAD) in pregnant vs. virgin rats. Anesthetized animals were ventil… Show more

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Cited by 5 publications
(3 citation statements)
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“…Administration of HES will increase venous return and cardiac output [28]. EF is greatly increased after HES infusion.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Administration of HES will increase venous return and cardiac output [28]. EF is greatly increased after HES infusion.…”
Section: Discussionmentioning
confidence: 99%
“…Echocardiographic examinations were repeated 20 min after MIL infusion. In the second experiment, after BL echocardiography, hydroxyethyl starch (HES) solution (6% Salinhes fluid solution, Fresenius Kabi Japan, Tokyo, Japan) was administered at a contrast rate of 5% of the total blood volume kg −1 min −1 , and the echocardiographic images were acquired when the volume of administered HES reached 60% of the total blood volume [28]. Total blood volume was estimated using the following equation [29,30]: BV (mL) = BW (gm) × 0.06 + 0.77 (1)…”
Section: Animal Preparation and Experimental Protocolmentioning
confidence: 99%
“…In a study of female Sprague–Dawley rats, right atrial dimensions increased in full‐term pregnant rats when compared to virgin rats to accommodate for the increase in plasma volume 45 . Electrical changes that predispose to arrhythmogenesis may be mediated through stretch‐activated channels 46 .…”
Section: Discussionmentioning
confidence: 99%