Right Ventricular Performance After Valve Repair for Chronic Degenerative Mitral Regurgitation

Abstract

Link to publication Citation for published version (APA): Hyllen, S., Nozohoor, S., Ingvarsson, A., Meurling, C., Wierup, P., & Sjögren, J. (2014). Right ventricular performance after valve repair for chronic degenerative mitral regurgitation. Annals of Thoracic Surgery, 98(6), 2023-2031. DOI: 10.1016/j.athoracsur.2014 General rights Copyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights.• Users may download and print one copy of any publication from the public portal for the purpose of private study or research.• You may not further distribute the material or use it for any profit-making activity or commercial gain • You may freely distribute the URL identifying the publication in the public portal Right Ventricular Performance Following Valve Repair for Chronic Degenerative Mitral Regurgitation

Right ventricular mechanical pattern in patients undergoing mitral valve surgery: a predictor of post‐operative dysfunction?

“…Importantly, the advanced 3D parameters of longitudinal RV function were predictors of post-operative RVD (pre-operative LEF: OR = 1.33 [95% CI: 1.08-1.77], P < 0.05; pre-operative 3D RVGLS: OR = 0.82 [95% CI: 0.68-0.94], P < 0.05). Despite their established prognostic value, 18,19 neither pre-operative LAESVi nor PASP (by echo) was predictive of RVD in our study cohort.…”

Impact and evolution of right ventricular dysfunction after successful MitraClip implantation in patients with functional mitral regurgitation

“…RV dysfunction represents a strong and independent predictor of mortality in left ventricular ischemic and non-ischemic heart failure (HF) [4], [5], [6], [7], [8], [9], [10]. Alternate effects of surgical mitral valve repair or replacement on preexisting RV dysfunction have been reported in different published series of patients [11], [12], [13], [14], [15], [16], [17], [18] Percutaneous mitral valve repair with MitraClip has been shown to be associated with a favorable clinical outcome and left and right ventricular reverse remodeling in high-risk patients with severe MR [19], [20], [21], [22]. In the present study we evaluated the impact and the evolution of pre-existing RV dysfunction in high-risk functional MR (FMR) patients after successful MitraClip implantation.…”

Unmasking right ventricular dysfunction in chronic rheumatic mitral regurgitation

“…RV functional impairment and decreased LVEF are powerful predictors of cardiovascular and overall survival in degenerative MR. 6 The main determinants of RV function in MR are RV load, myocardial function, neuro-hormonal abnormalities and ventricular interaction. 5,26 Only RV free-wall PSS was measured in this study as the interventricular septum contributes minimally to RV function.…”

“…STE has been shown to be advantageous over conventional echocardiographic parameters used to measure RV systolic function in a variety of cardiovascular disorders such as heart failure, pulmonary hypertension and pre-operative and postoperative RV function assessment. 6,11,12,13,28 This finding can be explained by technical aspects, as speckletracking is angle independent and less influenced by heart motion compared to TAPSE and RVS′. 1 Additionally, TAPSE and S′ only measure regional RV function, whereas RV free-wall PSS is able to provide more global assessment of RV function.…”

“…10,23,24 The region of interest, once created, can be manually adjusted as needed to allow for adequate speckle-tracking. 6 The RV free-wall PSS was obtained by averaging three lateral segments (the basal, mid and apical RV wall). 25 The interventricular septum was excluded from analysis.…”