2022
DOI: 10.3390/jcm11216558
|View full text |Cite
|
Sign up to set email alerts
|

Risk Factors Affecting Development and Persistence of Preschool Wheezing: Consensus Document of the Emilia-Romagna Asthma (ERA) Study Group

Abstract: Wheezing at preschool age (i.e., before the age of six) is common, occurring in about 30% of children before the age of three. In terms of health care burden, preschool children with wheeze show double the rate of access to the emergency department and five times the rate of hospital admissions compared with school-age asthmatics. The consensus document aims to analyse the underlying mechanisms involved in the pathogenesis of preschool wheezing and define the risk factors (i.e., allergy, atopy, infection, bron… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
4
1

Citation Types

0
11
0

Year Published

2023
2023
2024
2024

Publication Types

Select...
6

Relationship

1
5

Authors

Journals

citations
Cited by 11 publications
(11 citation statements)
references
References 263 publications
0
11
0
Order By: Relevance
“…Viral infections that induce a predominant Th2 response (like rhinovirus and RSV) are considered a risk factor for recurrent wheezing. 74,75 At COLAZO SALBETTI ET AL.…”
Section: Natural History Of Infection Pathophysiology and Clinical Fe...mentioning
confidence: 99%
See 3 more Smart Citations
“…Viral infections that induce a predominant Th2 response (like rhinovirus and RSV) are considered a risk factor for recurrent wheezing. 74,75 At COLAZO SALBETTI ET AL.…”
Section: Natural History Of Infection Pathophysiology and Clinical Fe...mentioning
confidence: 99%
“…76,77 On the other hand, transient low levels of IgG subclass 4 are associated with recurrent wheezing requiring multiple hospitalisations in childhood and IgA deficiency may predispose to recurrent respiratory infections and wheezing. 75,78 One report found HBoV1 at high frequency in infants with wheezing and low IgA and IgG4 levels, suggesting a possible involvement in recurrent wheezing during childhood. 79 However, the cytokine response in respiratory secretions and peripheral blood has been poorly approached, which encourages further research.…”
Section: Natural History Of Infection Pathophysiology and Clinical Fe...mentioning
confidence: 99%
See 2 more Smart Citations
“…Asthma is the most common chronic disease of childhood in the world, and asthma exacerbation is frequently caused by viral infections [ 11 , 12 ]. Initially, asthma patients were classified as an at-risk group for COVID-19 severe forms, but whether asthma has worse COVID-19 consequences is not yet clear [ 13 ].…”
Section: Incidence Of Sars-cov-2 Infection and Severity Of Disease In...mentioning
confidence: 99%