Risk factors affecting the prognosis of urinary tract infection in Chinese pediatric patients: Single‐center experience

Abstract

Background Urinary tract infection (UTI) is common in children. The purpose of this retrospective study was to determine the various risk factors that usually affect the prognosis of UTI in children diagnosed with the disease. Methods In the present retrospective study, we enrolled all pediatric patients diagnosed with UTI and hospitalized between 1 January 2013 and 31 July 2016 at Nanjing Children's Hospital. We then collected all the relevant patient clinical demographics and characteristics. Results The study involved 2,092 pediatric patients diagnosed with UTI. On logistic regression analysis, factors that could affect the prognosis of pediatric UTI were complications, hospitalization, intensive care unit (ICU) admission, type of UTI, urine culture results, blood lymphocytes, urine nitrites (NIT) and antibiotics (unstandardized coefficients, 0.06, <0.001, −0.28, 0.32, <0.001, 0.01, −0.11, 0.01, respectively, all P < 0.001). Conclusion Complications, hospitalization, type of UTI, urine culture results, blood lymphocytes, and antibiotics had a significant, positive association with UTI prognosis. Meanwhile, ICU admission and urine NIT had a negative association with prognosis.

Prediction Model for Urinary Tract Infection in Pediatric Urological Surgery Patients

“…We aimed to construct a multifactorial predictive model for the development of UTI in pediatric urological surgery patients, which could be applied as a simple predictive tool for identifying pediatric urological surgery patients at high risk of developing UTI and thereby applying preventive strategies for the modifiable factors. This study was the first predictive model for UTI in pediatric urological surgery patients in China, as previous studies performed in China focused on identification of the risk factors ( 13 – 15 ).…”