Risk Factors Associated With Symptomatic Deep Vein Thrombosis Following Elective Spine Surgery

Zervos, Thomas M; Bazydlo, Michael; Tundo, Kelly M; Macki, Mohamed; Rock, Jack

doi:10.1093/neuros/nyaa447_699

Cited by 3 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These clots can obstruct normal blood flow in affected vein, causing some clinical symptoms such as swelling, pain, and potentially severe complications. Patients with pulmonary embolism have the highest fatality rate [1]. Hip surgery affects blood flow to limbs, and DVT easily occurs due to impaired blood circulation [2].…”

Section: Introductionmentioning

confidence: 99%

Safety and efficacy of salvianolate injection in preventing deep vein thrombosis after total hip replacement

Liu,

Ju,

Yin

et al. 2023

Trop. J. Pharm Res

View full text Add to dashboard Cite

Purpose: To investigate the safety and efficacy of salvianolate injection in preventing deep vein thrombosis (DVT) following total hip replacement. Methods: A total of 114 patients who underwent total hip replacement at Department of Trauma, Fengfeng General Hospital of North China Medical and Health Group, Handan City, China from March 2019 to March 2022 were enrolled. Patients were randomly divided into study group (n = 57) and control group (n = 57). The control group received conventional treatment (low molecular weight heparin) while the study group was administered salvianolate injection combined with conventional treatment. Incidence of deep vein thrombosis (DVT) at 7 and 14 days after surgery, platelet function indices, including platelet count, glycoprotein Ⅱb/Ⅲa (GPⅡb/Ⅲa), and CD62P, coagulation function indices (prothrombin time (PT), fibrinogen (FIB) and D-dimer), and hemodynamics indices, viz, peak blood flow velocity (Vp) and average velocity (Va) were investigated and compared. Results: Incidence of DVT was 1.75 % (1/57) at 7 days and 5.26 % (3/57) at 14 days in the study group, and 5.26 % (3/57) at 7 days and 17.54 % (10/57) at 14 days in control group. Incidence of DVT in the study group was significantly reduced compared to control group 14 days after surgery (p < 0.05). Also, the study group had significantly lower visual analog scale (VAS) scores at 7 days and 1 month after surgery compared to control group (p < 0.05). Platelet count, GPⅡb/Ⅲa, and CD62P in the study group were significantly lower than in control group (p < 0.05). Conclusion: Salvianolate injection significantly prevents DVT after total hip replacement, improves hemodynamics, and coagulation function, and thus contributes to recovery of hip function. Further clinical trials are, however, required to validate these findings.

show abstract

Section: Introductionmentioning

confidence: 99%

Safety and efficacy of salvianolate injection in preventing deep vein thrombosis after total hip replacement

Liu,

Ju,

Yin

et al. 2023

Trop. J. Pharm Res

View full text Add to dashboard Cite

show abstract

“…However, in clinical practice, nursing staff still lack understanding of the LEDVT risk factor identification, the timing ofLEDVT risk assessment, and the correct use of the LEDVT risk assessment scales [ 8 ]. Coupled with a lack of authoritative unified clinical guidelines, all of which leads to inaccurate identification and risk stratification of the LEDVT risk factors in general surgical patients, as well as the negative prevention or excessive prevention is common, greatly affecting the perioperative rehabilitation of patients and the identification of potential risk of the LEDVT [ 9 ]. Therefore, an in-depth understanding of the risk factors for LEDVT occurrence, early identification, and accurate risk assessment are of great significance for the prevention and control of LEDVT in patients.…”

Section: Introductionmentioning

confidence: 99%

Analysis of Risk Factors for Postoperative Lower Extremity Deep Venous Thrombosis and its Treatment and Nursing

Liu

Peng

2022

Emergency Medicine International

View full text Add to dashboard Cite

Objective. To explore the risk factors of lower extremity deep venous thrombosis (LEDVT) after surgery and discuss the treatment and nursing countermeasures. Methods. A retrospective analysis was conducted on 268 surgical patients admitted between July to December 2021. The factors associated with LEDVT were analyzed using the Logistic regression model. Further, LEDVT patients were assigned to a research group treated with targeted nursing to prevent LEDVT and a control group that used routine care. Coagulation function and inflammatory cytokines before and after nursing intervention were compared between groups. The assessment of patients’ mobility employed the lower limb motor function part of the Fugel–Meyer Assessment (FMA), Harris Hip Score (HHS), and Barthel index (BI), and their psychological status was evaluated using the Kolcaba’s General Comfort Questionnaire (GCQ) and Self-rating Anxiety/Depression Scale (SAS/SDS). Finally, patient satisfaction with the treatment service was investigated. Results. Logistic regression analysis showed that hypertension, limb paralysis, central venous catheterization of lower limbs, and bedridden time affect postoperative LEDVT in an independent way ( P < 0.05 ). After the intervention, the coagulation function and inflammatory reaction were improved in both groups, with more significant improvement in the research group ( P < 0.05 ). The research group also showed higher FMA, Harris, GCQ, and BI scores while lower SAS and SDS scores than the control group postnursing intervention ( P < 0.05 ). Finally, a higher satisfaction rate was identified in the research group as compared to the control group ( P < 0.05 ). Conclusion. Hypertension, limb paralysis, CVC of lower limbs, and bedridden time are all independent risk factors for LEDVT after surgery. The implementation of targeted nursing strategies for the above factors can effectively alleviate the hypercoagulable state of patients after operation, reduce inflammatory responses, and improve patient comfort, which is of great significance for preventing the occurrence of LEDVT.

show abstract

To the Problem of Deep Vein Thrombosis of the Lower Extremities in the Postoperative Period

Morozov,

Sergeev,

Askerov

et al. 2023

Vrach

View full text Add to dashboard Cite

A review of foreign literature sources on the problem of postoperative development of deep vein thrombosis of the lower extremities is presented. The incidence of deep vein thrombosis of the lower extremities among patients who have undergone surgery depends on the type of surgery and risk factors to which the patient is exposed. Thrombosis is most likely to develop after open operations on large vessels, orthopedic and traumatological operations on the extremities. Of no small importance are blood counts, the presence of concomitant diseases such as hypertension, hypertension of the small circulatory circle, diabetes mellitus, osteoporosis and other chronic diseases. It is important to make a competent decision on surgical intervention, taking into account all the risk factors to which the patient is exposed, choosing an individual approach in the prevention of postoperative thrombosis.

show abstract

Risk Factors Associated With Symptomatic Deep Vein Thrombosis Following Elective Spine Surgery

Cited by 3 publications

References 0 publications

Safety and efficacy of salvianolate injection in preventing deep vein thrombosis after total hip replacement

Safety and efficacy of salvianolate injection in preventing deep vein thrombosis after total hip replacement

Analysis of Risk Factors for Postoperative Lower Extremity Deep Venous Thrombosis and its Treatment and Nursing

To the Problem of Deep Vein Thrombosis of the Lower Extremities in the Postoperative Period

Contact Info

Product

Resources

About