Risk factors associated with urinary tract infections in intensive care patients

Lee, Eng Kiang; Teo, Alvin; Land, Gillian; Borrell, Sue; Spelman, Denis; Leong, Tim; Cheng, Allen

doi:10.1016/j.idh.2016.03.004

Cited by 6 publications

(6 citation statements)

References 13 publications

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“…8,11 Previous studies done in various setting and hospital, like one study by Lee and colleagues in intensive care patients in Australia with 68% reported patients with symptomatic UTI were female. 9 But in this study, although female patient was indeed more than male, those who had positive urine culture tended to be male, even though not statistically significant. This result contradicting popular believe that female is more susceptible to UTI, it might due to our study population inclined to be patients aged over the fifth decades.…”

Section: Discussioncontrasting

confidence: 60%

Risk Factors for Urinary Tract Infection in Hospitalized Patients

Setyorini

Mardiana

Tjempakasari

2019

BHSJ

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Introduction: Urinary tract infection (UTI) is the most common infection that can be fatal and has higher rate mortality especially in some patient. This study is aim to analyze risk factors for urinary tract infection in hospitalized patients for prevention and more aggressive approach can be taken.Methods: Consecutively, medical records of 285 patients with urinary analysis was recorded for risk factors and urine culture results if suspected UTI. Risk factors for sex, age, urinary catheter, urolithiasis, DM, and immobilization was analyzed with bivariate analysis and multivariate analysis.Results: From 285 patients, 92 patients had UTI with average age was 52.45 years old, 48 (56.49%) were female. Most common pathogen were E. coli (41.3%), Enterobacter sp. (8.8%) and Enterococcus faecalis (7.6 %). From bivariate analysis, geriatric age (>60 years) has RR 1.421 (95% CI 1.015-1.989, p=0.046) and immobilization has RR 1.861 (95% CI 1.266-2.738, p=0.007), whereas sex (RR 1.190 95% CI 0.851 – 1.664, p=0.310), diabetes (RR 1.171 95% CI 0.833 – 1.645, p=0.367), insulin usage (RR 0.900 95% CI 0.519 – 1.561, p= 0.703), glycosuria (RR 1.152 95% CI 0.741 – 1.791, p=0.522), and CKD (RR 1.475 95% CI 0.896 – 2.430, p= 0.126) give insignificant result. From multivariate analysis, urinary catheter has OR 4.506 (95% CI 2.312-8.872, p=0.000), urolithiasis with OR 4.970 (95% CI 1.931-12.787, p=0.001), and hyperglycemia has OR 2.871 (95% CI 1.485-5.551, p=0.002).Conclusion: Geriatric age and immobilization are risk factors for urinary tract infection, and urinary catheter, urolithiasis, and hyperglycemia are independent risk factors for urinary tract infection.

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Section: Discussioncontrasting

confidence: 60%

Risk Factors for Urinary Tract Infection in Hospitalized Patients

Setyorini

Mardiana

Tjempakasari

2019

BHSJ

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“…Lee et al (2016) [10] and Liu et al (2018) [6] conducted a study to elaborate on different risk factors for urinary tract infections in intensive care unit patients. For this study, they compared UTI cases of ICU patients with an uninfected control group.…”

Section: Rationale Of Studymentioning

confidence: 99%

Onset of urinary tract infections in ICU patients

Mehrotra¹

2021

Int. J. Appl. Dent. Sci.

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Background: Urinary tract infections are widespread among intensive care unit patients than in the general population. But what makes the occurrence of UTIs more common in ICU patients? Although studies about the prevalence of urinary tract infections are available, significantly less data is available on the onset of UTIs in intensive care units. Therefore, we aimed this study to evaluate the prevalence of urinary tract infections in ICU patients. We also tried to find out different risk factors and their possible solutions. Aims and Objectives Risk factors involved in the onset of urinary tract infections in ICU patients To make recommendations based on the study Materials and MethodsThe primary target audience in our research work is particularly, i.e. intensive care unit patients. Therefore, we decided to collect data from 3 intensive care units from three hospitals. We also included a questionnaire for physicians to know their points of view about the issue. Finally, we collected data and compiled it in MS Excel for further processing. Results: The prevalence of the population was found to be very high. Almost forty per cent was recorded. Conclusion: Cleanliness, hygiene and proper sterilization is needed and is the need of the hour.

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“…The BALB/c mice are used as an experimental animal because the simiarities in the reaction towards the disease, treatment, and physiological condition with human. 9 The P. berghei ANKA parasites has been widely used for research on the development of anti-malarial drugs with various plant extracts. 10,11 This research was conducted considering the number of cases of resistance of plasmodium parasites to anti-malarial drugs such as chloroquine pyrimethamine-sulfadoxine and quinine.…”

Section: Introductionmentioning

confidence: 99%

Antimalarial Activity of Ethanol Extract of Noni Leaves (Morinda citrifolia) towards Parasitemia, Splenomegaly, and Hepatomegaly in Plasmodium berghei ANKA Infected Mice

Rahayu

Hernaningsih

Arwati

2021

BHSJ

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Introduction: Malaria is one of the infectious diseases found in tropical countries and sub-tropical countries. In 2016 there were an estimated 445,000 people died to malaria. Alternative medicine is needed, such as natural based ingredient. Morinda citrifolia or noni plant is a medicinal plant found in all parts of Indonesia which has many benefits, such as antibacterial, analgesic, anticancer, antioxidant, and anti-inflammatory. The aims of this study were to determine the antimalarial activity of ethanol extract of noni leaves and its effect on splenomegaly and hepatomegaly.Methods: Extract of noni leaves was prepared by maceration using ethanol solvent. In vivo experiments were conducted using Plasmodium berghei infected BALB/c mice treated with the doses of 100, 10, 1 mg/kg body weight(BW) orally of ethanolic extract of noni leaves. Then, the percentage of parasitemia was calculated from day 1 to day 4 after treatment and at the end of the test, mice were sacrificed then spleen and liver were collected. Results: The highest parasite growth was found in the group treated with noni leaves ethanol extract at a dose of 1 mg/kg WB and vice versa. Probit analysis resulted in ED50 was 0.882 mg/kg WB. Spearmen test showed there was no correlation between doses and the size of splenomegaly with p=0,2 and between doses and the size of hepatomegaly with p=0,6.Conclusion: Ethanol extract of noni leaves possessed antimalaria activity and there was no correlation between doses of extract and t he splenomegaly and hepatomegaly.

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Risk factors associated with urinary tract infections in intensive care patients

Cited by 6 publications

References 13 publications

Risk Factors for Urinary Tract Infection in Hospitalized Patients

Risk Factors for Urinary Tract Infection in Hospitalized Patients

Onset of urinary tract infections in ICU patients

Antimalarial Activity of Ethanol Extract of Noni Leaves (Morinda citrifolia) towards Parasitemia, Splenomegaly, and Hepatomegaly in Plasmodium berghei ANKA Infected Mice

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