Risk factors for aortic complications in adults with coarctation of the aorta

Oliver, José M.; Gallego, Pastora; González, Ana; Aroca, Ángel; Bret, M; Mesa, José Marı́a

doi:10.1016/j.jacc.2004.07.037

Cited by 180 publications

(86 citation statements)

References 29 publications

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“…93 Second, a history of concomitant aortic coarctation, corrected or uncorrected, indicates more diffuse aortopathy with increased risk for dissection or rupture. 114,115 Third, a family history of aortic dissection or rupture in a first-degree relative may indicate inheritance of a more severe genotype. Fourth, a long smoking history, especially with chronic obstructive pulmonary disease, should prompt earlier intervention because smoking causes elastin fragmentation, and both smoking and chronic obstructive pulmonary disease correlate with larger aortic size and faster aortic expansion rate.…”

Section: Elective Surgical Repair or Replacement Of The Aortic Root Amentioning

confidence: 99%

Ascending Aortic Dilatation Associated With Bicuspid Aortic Valve

2009

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Section: Elective Surgical Repair or Replacement Of The Aortic Root Amentioning

confidence: 99%

Ascending Aortic Dilatation Associated With Bicuspid Aortic Valve

2009

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“…In patients with coarctation of the aorta elastic properties are primarily impaired and remain unchanged even years after successful operation; 11,49 recent studies on adults with coarctation repair have shown that age and bicuspid aortic valve are the main risk factors for wall complications in the long-term follow up period. 50 …”

Section: Discussionmentioning

confidence: 99%

Elastic Properties of the Ascending Aorta in Healthy Children and Adolescents

Hauser

Kühn

Petzuch

et al. 2013

Circ J

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Background:Compliance of the aorta is important in maintaining normal cardiovascular physiology. Pathological conditions can induce changes in elastic properties, having profound effects on their prognosis. The aim of this study was to establish age-related reference values for distensibility and wall stiffness index of the ascending aorta. Methods and Results:A total of 165 normal subjects (mean age, 11.92±4.0 years) were investigated on transthoracic echocardiography. Ascending aortic diameter was recorded in M-mode above the sinotubular junction. Blood pressure was measured simultaneously at the right arm. Aortic pulse pressure, distensibility and aortic wall stiffness index were calculated offline. Distensibility decreased significantly with age (r=−0.462, P<0.001); the regression line indicated an average decrease of 5.1 10 −3 kPa −1 (95% confidence interval [CI]: 3.9-6.8 10 −3 kPa −1 ) per year. Significant correlations could be found between distensibility and weight, height, body surface area (BSA) and body mass index (BMI) (P<0.001). Stiffness index increased significantly with age (r=0.399, P<0.001); the regression line indicated an average increase of 0.066 (95% CI: 0.047-0.085) per year; significant correlations could be found between wall stiffness index and weight, height, BSA and BMI (P<0.001). The 2.5th and 97.5th percentiles of the distribution of distensibility and stiffness index related to age, weight, height, BSA and BMI were calculated. Conclusions:Normal values of arterial elastic properties throughout childhood and adolescence have been provided, and might serve as a reference for individuals with cardiovascular and metabolic disease. (Circ J 2013; 77: 3007 -3014)

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“…However, aneurysm surgical site may occur in 50% of patients, particularly when using the flap dacron [2]. A variety of anatomical aneurysms indicates several mechanisms influencing its development.…”

Section: Aocmentioning

confidence: 99%