“…1 The lungs of habitual smokers are damaged by recurrent episodes of respiratory bronchiolitis, which finally lead to chronification and centrilobular emphysema. 2 Conventional pulmonary function testing (PFT), which is a global testing, does not allow early detection of chronic bronchiolitis and obstructive changes in small airways. Also, routine chest X-ray is not sensitive enough for detecting such early functional changes in the peripheral bronchial system.…”