Risk factors for failed transverse sinus stenting in pseudotumor cerebri patients

Current concepts in pseudotumor cerebri

“…Restenting rates are relatively low [36]. Stenting is followed by anticoagulation, which can complicate secondary management if unsuccessful [40]. Both dual antiplatelet therapy and warfarin have been used, which can increase the risk of intracranial and retrobulbar hemorrhage with shunting and ONSF, respectively [40,34 & ].…”

Letter regarding article ‘Focal stenosis of the sigmoid sinus causing intracranial venous hypertension: Case report, endovascular management and review of the literature’

“…As an accurate differentiation of these two underlying mechanisms is still not available, we cannot know which processes had been improved by the endovascular treatment method in this referenced review. 3 Although there are a large number of patients reported to respond to endovascular treatments in the literature, several cases have also been reported to fail with stent therapy 4 ; hence, the question of which patient will benefit from the endovascular process or CSF diversion methods remains unclear. On the other hand, in our unique report, we demonstrated multiple times (4 times) the relapse of transverse sinus stenosis and recovery of stenosis after lumbar punctures in a medically resistant patient with IIH.…”

Corticosteroids and Anti-Complement Therapy in Retinal Diseases

“…Treatment of CVST includes the use of systemic anticoagulation or venous sinus stenting, both of which have potential serious complications (Goodwin et al 2014;Subramanian and Haq 2014). The incidence of IIH is thought to be 1-3 per 100,000 people per year and is more common in females aged 20-40 (Friedman 2014).…”

“…Surgical therapy has included optic nerve sheath fenestration, lumboperitoneal shunting, ventriculoperitoneal shunting, and bariatric surgery for weight loss (Fridley et al 2011;Goodwin et al 2014;Lai et al 2014;Levin et al 2015;Menger et al 2014). Again success with these therapies ) has been reported in case series without the benefit of randomization.…”