Risk factors for life-threatening ischemic events and death in patients with myocardial infarction

Abstract

The development and implementation of effective measures of secondary prevention of recurrent ischemic events and post-hospital mortality in patients with myocardial infarction remains relevant. A total of 130 patients (89 men and 41 women) with myocardial infarction of type I were examined. At the in-patient stage of treatment, a set of laboratory data characterizing endogenous intoxication syndrome was subjected to clustering. As a result, four clusters were formed: polymarker-retentive, necrotic-inflammatory, hypoxic-inflammatory and a cluster with no endogenous intoxication syndrome. Recurrent heart attack, stroke, and mortality from cardiac causes constituted the combined end point. The probability of its occurrence within 1 year after myocardial infarction development was 18.6 %. We proposed a model for predicting the development of the combined endpoint, taking into account the type of endogenous intoxication syndrome.