Risk factors for low back pain: insights from a novel case-control twin study

Oliveira, Vinícius Cunha; Ferreira, Manuela L; Refshauge, Kathryn M.; Maher, Christopher G.; Griffin, Alexandra R; Hopper, John L.; Ferreira, Paulo H.

doi:10.1016/j.spinee.2014.06.021

Cited by 14 publications

(13 citation statements)

References 29 publications

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“…The co-twin control model is a type of twin differences model that focuses exclusively on MZ pairs who are discordant either for a disease or for an exposure, such as an environmental factor. This model has recently been used to investigate environmental contributions to the associations between BMI and cardiovascular disease (Song et al, 2015), between height and asthma (Protudjer et al, 2015) and between pain risk factors and low back pain (Oliveira et al, 2015). One notable study with this design demonstrated that smoking was associated with a reduction of 5-10% in bone density, thereby conferring a high risk of fracture (Hopper & Seeman, 1994).…”

Section: Twin Differences Modelsmentioning

confidence: 99%

The Value of Twins for Health and Medical Research: A Third of a Century of Progress

et al. 2020

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In 1984, Hrubec and Robinette published what was arguably the first review of the role of twins in medical research. The authors acknowledged a growing distinction between two categories of twin studies: those aimed at assessing genetic contributions to disease and those aimed at assessing environmental contributions while controlling for genetic variation. They concluded with a brief section on recently founded twin registries that had begun to provide unprecedented access to twins for medical research. Here we offer an overview of the twin research that, in our estimation, best represents the field has progress since 1984. We start by summarizing what we know about twinning. We then focus on the value of twin study designs to differentiate between genetic and environmental influences on health and on emerging applications of twins in multiple areas of medical research. We finish by describing how twin registries and networks are accelerating twin research worldwide.

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Section: Twin Differences Modelsmentioning

confidence: 99%

The Value of Twins for Health and Medical Research: A Third of a Century of Progress

et al. 2020

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“…7,9 It is known that the majority of people with lumbago deal with it themselves, 29 whereas the main preventative measures reside in the approach of seeking professional help and treatment as soon as the first symptoms appear. 7 The OLBPYQ is also aimed at generating data capable of fostering greater discussion concerning the associated risk factors, and thus, as suggested by other studies, questions concerning physical activity, 21,33,34 time spent playing computer games/ watching videos and TV, 21,32,34 gender, 21,34 sleeping time 31 and others, were included. The Oliveira questionnaire on low back pain in young people showed adequate reliability.…”

Section: 13mentioning

confidence: 99%

Reliability, Stability and Validity of the Brazilian Adaptation of the Oliveira Questionnaire on Low Back Pain in Young People

et al. 2017

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The objective of this study was to adapt the Brazilian version, and verify the validity, reliability and internal consistency of the Oliveira questionnaire on low back pain in young people. Material and Methods:The questionnaire was translated from European Portuguese into Brazilian Portuguese by means of translation and re-translation. The validity of the contents was determined by experts who analyzed the clarity and pertinence of the questions. Fifteen young people aged 15 to 18 took part in the pre-test step (qualitative analysis), 40 in the test-retest (reliability) and 679 in the evaluation of internal consistency. The intra-class correlation coefficient and Spearman's correlation coefficient were used in the reliability analysis (test-retest), and Cronbach's alpha to determine the internal consistency (stability). Results:In the translation phase the questionnaire was modified and considered suitable, observing similarity and equivalence of the two versions. After being corrected by the experts in the validation of the contents, the instrument was considered suitable and valid, and in the pre-test, the young people suggested some modifications to make the questionnaire more succinct. With respect to reliability, the values for the intra-class correlation coefficient were between 0.512 -acceptable and 1 -excellent and Spearman's correlation coefficient varied between 0.525 and 1, classifying the instrument as reproducible. The internal consistency was considered acceptable with a 0.757 Cronbach's alpha. Discussion: The Oliveira questionnaire was choosen since it has been used in several Portuguese studies; moreover, it addresses the need to raise data regarding low back pain and associated risk factors. Conclusions:The Brazilian version of the Oliveira questionnaire on low back pain in young people showed valid and reliable cultural adaptation, with good reliability and stability.

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“…The BTR (www.gemeosbrasil.org) was born as a result of the interest of Brazilian researchers undertaking twin rereceived 20 September 2016; accepted 22 September 2016 address for correspondence: Paulo H. Ferreira, Faculty of Health Sciences, Cumberland Campus, University of Sydney, 75 East St, Sydney NSW 1875, Australia. E-mail: paulo.ferreira@sydney.edu.au search in Australia, mainly in the field of musculoskeletal pain (Dario et al, 2016;Ferreira et al, 2011;Ferreira et al, 2013;Ferreira et al, 2016;Junqueira et al, 2014;Oliveira et al, 2015;Pinheiro et al, 2015). Since its inception, the BTR has been fully supported by the Australian Twin Registry and could be regarded as its co-twin registry.…”

Section: A Brief History Of the Btrmentioning

confidence: 99%

The Brazilian Twin Registry

et al. 2016

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The Brazilian Twin Registry (BTR) was established in 2013 and has impelled twin research in South America. The main aim of the initiative was to create a resource that would be accessible to the Brazilian scientific community as well as international researchers interested in the investigation of the contribution of genetic and environmental factors in the development of common diseases, phenotypes, and human behavior traits. The BTR is a joint effort between academic and governmental institutions from Brazil and Australia. The collaboration includes the Federal University of Minas Gerais (UFMG) in Brazil, the University of Sydney and University of Melbourne in Australia, the Australian Twin Registry, as well as the research foundations CNPq and CAPES in Brazil. The BTR is a member of the International Network of Twin Registries. Recruitment strategies used to register twins have been through participation in a longitudinal study investigating genetic and environmental factors for low back pain occurrence, and from a variety of sources including media campaigns and social networking. Currently, 291 twins are registered in the BTR, with data on demographics, zygosity, anthropometrics, and health history having been collected from 151 twins using a standardized self-reported questionnaire. Future BTR plans include the registration of thousands of Brazilian twins identified from different sources and collaborate nationally and internationally with other research groups interested on twin studies.

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Risk factors for low back pain: insights from a novel case-control twin study

Cited by 14 publications

References 29 publications

The Value of Twins for Health and Medical Research: A Third of a Century of Progress

The Value of Twins for Health and Medical Research: A Third of a Century of Progress

Reliability, Stability and Validity of the Brazilian Adaptation of the Oliveira Questionnaire on Low Back Pain in Young People

The Brazilian Twin Registry

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