2001
DOI: 10.1016/s0002-9343(01)00770-7
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Risk factors for visual loss in giant cell (temporal) arteritis: a prospective study of 174 patients

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Cited by 197 publications
(121 citation statements)
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“…Cranial ischemic complications were reported at presentation in 25% of this group of GCA patients (visual loss in 18% and stroke in 7%). These values are comparable with the rates described in other studies (20,21,23). Regarding cranial ischemic complications developing after initiation of steroid therapy and during followup, the rates of visual loss and CVA in our patients were 5% and 4%, respectively.…”
Section: Discussionsupporting
confidence: 91%
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“…Cranial ischemic complications were reported at presentation in 25% of this group of GCA patients (visual loss in 18% and stroke in 7%). These values are comparable with the rates described in other studies (20,21,23). Regarding cranial ischemic complications developing after initiation of steroid therapy and during followup, the rates of visual loss and CVA in our patients were 5% and 4%, respectively.…”
Section: Discussionsupporting
confidence: 91%
“…Previous studies have suggested that the rate of cranial ischemic complications is inversely related to the intensity of the inflammatory response (10,20,21). Another study showed an increased rate of visual loss in patients with thrombocytosis (21).…”
Section: Discussionmentioning
confidence: 99%
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“…In our series, the proportion of patients who developed permanent visual loss (19.1%) was similar to that reported by Gonzalez-Gay et al (2,12) and by Cid et al (9) (2,3,9,11). Although geographic and ethnic factors may be implicated in the differences in the incidence of GCA at different latitudes, they do not seem to influence the expression of visual manifestations.…”
Section: Discussionsupporting
confidence: 90%
“…In a study from Spain, the presence of a strong acute-phase response (fever and weight loss, ESR 85 mm/ hour, Hgb Ͻ11 gm/dl) at diagnosis defined a subgroup of patients at very low risk of developing cranial ischemic events (in particular visual loss) (9). Likewise, in the study of Liozon et al (11), patients with visual loss had significantly less marked constitutional symptoms and lower CRP levels. Furthermore, similarly to our study, an increased risk of developing visual loss was observed in patients with thrombocytosis at diagnosis.…”
Section: Discussionmentioning
confidence: 96%