Risk Factors, Onset, and Progression of Epiretinal Membrane after 25-Gauge Pars Plana Vitrectomy for Rhegmatogenous Retinal Detachment

Ishida, Yusuke; Iwama, Yasuaki; Nakashima, Hiroshi; Ikeda, Toshihide; Emi, Kazuyuki

doi:10.1016/j.oret.2019.10.004

Cited by 29 publications

(32 citation statements)

References 21 publications

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“…Similar to our study, preoperative VH was previously reported in both prospective and retrospective studies as a risk factor for macular pucker after RRD surgery 1 , 3 , 6 . Hagler & Aturaliya demonstrated that 15 of 44 eyes with macular pucker (34%) had VH 7 .…”

Section: Discussionsupporting

confidence: 92%

“…Moreover, the development of macular pucker and background clinical characteristics are interrelated, and one-to-one univariate analyses do not allow for an independent assessment of the association between background clinical characteristics and macular packer formation. Although a previous prospective study reported the risk factor of macular pucker by multivariate analysis, some characteristics have not been assessed as potentially correlated with outcomes 6 , such as past history of laser photocoagulation, preoperative lens status, use of a scleral buckle, use of silicone oil tamponade, and intraoperative complications.…”

Section: Introductionmentioning

confidence: 99%

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Risk factors for macular pucker after rhegmatogenous retinal detachment surgery

Hirakata

Hiratsuka

Yamamoto

et al. 2021

Sci Rep

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Macular pucker, also known as an epiretinal membrane, sometimes forms after surgical repair of a rhegmatogenous retinal detachment (RRD) and can decrease visual acuity and cause aniseikonia. However, few reports are evaluating the risk factors of macular pucker using multivariate analysis. To evaluate the risk factors for macular pucker after RRD surgery, 226 patients who underwent RRD surgery and were monitored for greater than 12 months (23.2 ± 6.4 months) after surgery were analyzed retrospectively. Of these cases, macular pucker developed in 26 cases. Multiple logistic regression models of 22 clinical characteristics were performed. An increased risk of macular pucker after RRD surgery was significantly associated with preoperative vitreous haemorrhage (Odds ratio (OR), 4.71; 95% CI 1.19–18.62), multiple retinal breaks (OR, 8.07; 95% CI 2.35–27.71), re-detachment (OR, 19.66; 95% CI 4.87–79.38), and retinal detachment area (OR, 12.91; 95% CI 2.34–71.19). Macular pucker was not associated with the surgical technique. Regardless of the surgical technique used, careful observation for postoperative macular pucker is needed after RRD surgery in high-risk cases. These findings can be used to improve the surgical management of patients with RRD. (183 words).

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Section: Discussionsupporting

confidence: 92%

Section: Introductionmentioning

confidence: 99%

Risk factors for macular pucker after rhegmatogenous retinal detachment surgery

Hirakata

Hiratsuka

Yamamoto

et al. 2021

Sci Rep

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show abstract

“…In patients with OGI, the presence of retinal injury, IOFBs, and vitreous hemorrhage increases the risk of ERM by inducing production of cytokines and various growth factors and promoting RPE cell dissemination [ 22 , 23 ]. An observational study suggested that the average time for development of an ERM after PPV in patients with ocular trauma was 55.23 days (range, 29–72 days) [ 24 ].…”

Section: Discussionmentioning

confidence: 99%

Internal Limiting Membrane Peeling versus Nonpeeling to Prevent Epiretinal Membrane Formation following Vitrectomy for Posterior Segment Open-Globe Injury

Wei

Zhong

et al. 2021

Journal of Ophthalmology

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Purpose. Approximately 30% of patients with an open-globe injury (OGI) develop a secondary epiretinal membrane (ERM). This study was performed to assess whether internal limiting membrane (ILM) peeling in the treatment of posterior segment OGI prevents ERM formation. Methods. The medical records of 33 patients who underwent vitrectomy for posterior segment OGI from 2016 to 2019 were retrospectively analyzed. Of these patients, 17 underwent ILM peeling during the vitrectomy and 16 did not. The patients’ demographic and surgical data were collected. The associations of ILM peeling with the preoperative findings of posterior segment OGI and development of a postoperative ERM were analyzed. Student’s t-test was used to evaluate differences in continuous variables, and the chi-squared test or Fisher’s exact test was used for categorical variables. Time-to-event curves were calculated from postestimation Cox proportional hazards models. Results. An ERM developed in three eyes (17.6%) in the ILM peeling group and in eight eyes (50.0%) in the nonpeeling group ( p < 0.05 ). There was no statistically significant difference between the groups in visual acuity at baseline (1.68 vs. 1.58 logMAR, p = 0.68 ) or at final follow-up (0.72 vs. 0.78 logMAR, p = 0.66 ). Median visual acuity significantly improved in both groups ( p < 0.001 ). In the multivariable models, ILM peeling (odds ratio, 0.19; 95% confidence interval, 0.04–0.91; p = 0.04 ) and worse preoperative vision (odds ratio, 0.29; 95% confidence interval, 0.10–0.80; p = 0.02 ) were associated with lower likelihood of ERM formation. Conclusion. Preventative treatment with ILM peeling contributed to decreased development of an ERM in patients with OGI involving areas near the fovea.

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“…Daher kann der Einsatz von schwerer Flüssigkeit oder eine bimanuelle Vorgehensweise mit zusätzlichen Instrumenten unter Einsatz von Chandelier-Beleuchtungssystemen sinnvoll sein. Da die vollständige Entwicklung eines "macular pucker" nach vorangegangenem Ereignis meist über einen Zeitraum von 6 bis 12 Wochen erfolgt und die Operation idealerweise dann erfolgen sollte, wenn die Membran sich nicht mehr progredient traktiv zeigt, kann eine Verzögerung des Operationszeitpunktes hilfreich sein [14,15,58].…”

Section: Operationstechnikenunclassified

“…Bei adäquater chirurgischer Therapie von Patienten mit "macular pucker" nach Netzhautrissen oder Netzhautablösung kann in 65-90 % der Fälle ein Anstieg von 1 bis 2 Visusstufen erreicht werden, wobei für die Visusprognose entscheidend ist, ob zuvor eine Makulabeteiligung der Amotio retinae bestanden hatte [14,15,58].…”

Section: Operationstechnikenunclassified

Stellungnahme von BVA, DOG und RG zur Entwicklung, Diagnostik und Behandlung der epiretinalen Gliose

2021

Klin Monbl Augenheilkd

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Risk Factors, Onset, and Progression of Epiretinal Membrane after 25-Gauge Pars Plana Vitrectomy for Rhegmatogenous Retinal Detachment

Cited by 29 publications

References 21 publications

Risk factors for macular pucker after rhegmatogenous retinal detachment surgery

Risk factors for macular pucker after rhegmatogenous retinal detachment surgery

Internal Limiting Membrane Peeling versus Nonpeeling to Prevent Epiretinal Membrane Formation following Vitrectomy for Posterior Segment Open-Globe Injury

Stellungnahme von BVA, DOG und RG zur Entwicklung, Diagnostik und Behandlung der epiretinalen Gliose

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