Risk for Acute Renal Failure in Patients Hospitalized for Decompensated Congestive Heart Failure

Chittineni, Harini; Miyawaki, Nobuyuki; Gulipelli, Sailaja; Fishbane, Steven

doi:10.1159/000099012

Cited by 56 publications

(46 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…attention has recently been paid to the interaction between the heart and kidney, termed cardiorenal syndrome, because of its association with adverse outcomes [1][2][3]. Several studies have suggested that worsening of renal function during aDHF therapy is one of the most powerful predictors of mortality [4][5][6][7][8][9]. However, after the exclusion of several biases, an increase in serum creatinine level has been shown to have little impact on mortality in patients with aDHF [10][11][12][13][14][15].…”

Section: Introductionmentioning

confidence: 99%

Impact of onset time of acute kidney injury on outcomes in patients with acute decompensated heart failure

et al. 2014

View full text Add to dashboard Cite

Since acute kidney injury (AKI) is not always related to mortality in patients with acute decompensated heart failure (ADHF), the aim of this study was to focus on onset time of AKI and its clinical importance. A total of 371 ADHF patients were included. The impact of AKI (≥ 0.3 mg/dl or 1.5-fold increase in serum creatinine level within 48 h) with early onset (≤ 4 days from admission) or late onset (≥ 5 days from admission) was assessed. AKI occurred in 99 patients, who were divided into two groups according to the median onset time of AKI: 50 with early onset of AKI and 49 with late onset of AKI. The maximum increase in serum creatinine level from admission was greater in patients with late onset of AKI than in patients with early onset of AKI (p = 0.012). Patients with late onset of AKI had a higher 12-month mortality rate than that in patients with early onset of AKI (log-rank test, p = 0.014). Late onset of AKI was an independent predictor of mortality (hazard ratio: 3.39, 95 % confidence interval: 1.84-6.18, p < 0.001). Late onset of AKI was associated with high blood urea nitrogen level at admission and intravenous administration of dobutamine. In conclusion, late onset of AKI related to high blood urea nitrogen level and intravenous administration of dobutamine, but not early onset of AKI, is linked to high mortality rate. Onset time of AKI may be useful for risk stratification of mortality in ADHF patients developing AKI.

show abstract

Section: Introductionmentioning

confidence: 99%

Impact of onset time of acute kidney injury on outcomes in patients with acute decompensated heart failure

et al. 2014

View full text Add to dashboard Cite

show abstract

“…From an economical point of view, these outcomes result in a continuously growing burden on in-hospital and posthospitalization resources [17], demanding a new preventive and therapeutic approach. Identification of new risk factors, such as the presence of anemia at hospital admission, in addition to the further investigation of well-established risk factors [18,19,20,21,22,23,24,25,26], is essential for AKI prevention [18]. …”

Section: Discussionmentioning

confidence: 99%

Is Anemia at Hospital Admission Associated with In-Hospital Acute Kidney Injury Occurrence?

Shema-Didi

Ore²,

Geron³

et al. 2010

Nephron Clin Pract

View full text Add to dashboard Cite

Background: The effect of acute kidney injury (AKI) on anemia has been well-documented. However, the effect of ‘preexisting’ anemia on AKI has been less addressed. The aims of the present study were to investigate (1) the association between anemia at hospital admission and AKI occurrence, and (2) the effect of ‘preexisting’ anemia on the clinical outcomes of AKI. Methods: A retrospective cohort study was undertaken among patients aged ≧17 years who were admitted to our hospital during the year 2006 (n = 34,802). Anemia at hospital admission and AKI occurrences were determined using the WHO definition and the RIFLE criteria, respectively. A subgroup of patients with an estimated glomerular filtration rate ≧60 ml/min/1.73 m² was analyzed separately to control for the effect of chronic kidney disease on anemia. Results: The cumulative incidence of AKI was 11.2% in anemic patients at hospital admission, compared to 5.5% in nonanemic subjects. The association between anemia at admission and AKI occurrence remained statistically significant after controlling for potential confounders (odds ratio 1.5, 95% CI 1.4–1.6). In addition, an association between anemia at hospital admission and clinical outcomes of AKI was observed. Conclusion: Anemia at hospital admission should be recognized as a potential risk factor for in-hospital AKI occurrence.

show abstract

“…An increase in serum creatinine level is observed in 21-45% of patients admitted with acute decompensated HF (74)(75)(76)(77). Activation of RAAS and SNS due to reduced cardiac output volume and the effects of increased intraabdominal pressure (IAB) on the kidney are thought to be the causative mechanisms (24).…”

Section: How Does Peritoneal Dialysis Affect Glomerular Filtration Rate?mentioning

confidence: 99%

Role of Peritoneal Ultrafiltration in Heart Failure Treatment

Senel¹,

Cebeci²,

Öztürk³

2017

Haseki

View full text Add to dashboard Cite

Risk for Acute Renal Failure in Patients Hospitalized for Decompensated Congestive Heart Failure

Cited by 56 publications

References 33 publications

Impact of onset time of acute kidney injury on outcomes in patients with acute decompensated heart failure

Impact of onset time of acute kidney injury on outcomes in patients with acute decompensated heart failure

Is Anemia at Hospital Admission Associated with In-Hospital Acute Kidney Injury Occurrence?

Role of Peritoneal Ultrafiltration in Heart Failure Treatment

Contact Info

Product

Resources

About