2019
DOI: 10.1101/845644
|View full text |Cite
Preprint
|
Sign up to set email alerts
|

RNA sequencing and lipidomic analysis of alveolar macrophages from normal and CD44 deficient mice

Abstract: ABSTRACTAlveolar macrophages (AMs) are CD44 expressing cells that reside in the alveolar space where they maintain lung homeostasis by serving critical roles in immunosurveillance and lipid surfactant catabolism. AMs lacking CD44 are unable to bind the glycosaminoglycan, hyaluronan, which compromises their survival and leads to reduced numbers of AMs in the lung. Using RNA sequencing, lipidomics and multiparameter flow cytometry, we demonstrate that CD44-/- Show more

Help me understand this report
View published versions

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Publication Types

Select...

Relationship

0
0

Authors

Journals

citations
Cited by 0 publications
references
References 53 publications
0
0
0
Order By: Relevance

No citations

Set email alert for when this publication receives citations?