This year, we are facing a pandemic that has caused a catastrophe in the lives of people all over the world. In December of 2019, an outbreak of a novel coronavirus first emerged in the city of Wuhan which is in Hubei province of China. The virus has been named as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the disease as coronavirus disease 2019 because it causes sars and the disease was first discovered in the year 2019. In India though, the first lab-confirmed case of COVID-19 was first reported from the state of Kerala on January 30, 2020. As of March 31, 2020, a total 2,245 number of cases and 56 deaths were reported in India. Pathophysiology: Although this virus usually first invades the lung tissue and respiratory tract and causes pneumonia, and in severe cases, all the major organ systems in the body are impacted negatively causing to systemic failure in certain individuals. Alas, currently, there is no effective treatment for COVID. People with comorbidities, age and pathological sates are more prone to severe infection and finally, death. In this article, the mechanism at the cellular level and effects of COVID-19 to the human body. Factors like age immunity regular physical activity social distancing basic hygiene will be reviewed in this article. The objectives of this article are to first understand how the covid 19 virus affects various organ systems of the body. Then how routine physical activity is helpful in fighting the virus. And finally, what are the various ways in which we adapt routine physical activities in our daily lives during this lowdown and also look at the various physical activities.