Robot-Assisted Laparoscopic Partial Nephrectomy<i>Vs</i>Conventional Laparoscopic Partial Nephrectomy: Functional and Surgical Outcomes of a Prospective Single Surgeon Randomized Study

Würnschimmel, Christoph; Pierro, Giovanni Battista Di; Moschini, Marco; Grande, Pietro; Baumeister, Philipp; Roth, Manuel; Mordasini, Livio; Mattei, Agostino

doi:10.1089/end.2020.0143

Cited by 20 publications

(37 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The remaining 51 studies were included in this review ( Figure 1 ). Table 1 shows the characteristics of the included studies [ 8 – 58 ].…”

Section: Resultsmentioning

confidence: 99%

“…Forty-three of 51 were single centre studies, 46 were retrospective mono or multicentre, and 5 were prospective monocentre; 1 study was randomized [ 58 ] ( Table 1 ). Each study reported one or more surgical technique for NSS, comparing them in terms of surgical results and functional outcomes.…”

Section: Resultsmentioning

confidence: 99%

“…Thirty-three studies used at least one nephrometry score to assess for tumor complexity. In particular, 30 studies used the RENAL score, distinguishing or not between the types of ischemia [ 19 , 21 , 22 , 25 , 26 , 28 , 29 , 30 , 32 , 33 , 35 – 38 , 40 , 42 – 46 , 48 , 49 , 51 – 58 ]. Across the studies, RENAL score ranged from 5 to 9, with a mean value of 7.3.…”

Section: Resultsmentioning

confidence: 99%

“…Across the studies, RENAL score ranged from 5 to 9, with a mean value of 7.3. Four studies used the Padua score, which ranged from 6 to >10 ( Table 1 ) [ 34 , 39 , 50 , 58 ].…”

Section: Resultsmentioning

confidence: 99%

“…OPN was employed in 15 studies, including a total of 3940 cases [ 8 – 11 , 13 , 15 – 18 , 25 , 32 , 46 , 51 , 55 , 56 ], whereas LPN was applied in 27 studies, with a total of 2812 cases [ 9 – 12 , 14 , 16 – 25 , 27 , 30 , 31 , 39 , 45 , 48 , 49 , 55 – 58 ]. RAPN was analysed in 37 studies, comprising a total of 5661 cases ( Table 2 ) [ 18 , 20 , 21 , 22 , 24 – 29 , 31 – 38 , 40 – 58 ]. All the studies reported enucleoresection as the excision technique for PN ( Figure 2A ).…”

Section: Resultsmentioning

confidence: 99%

See 4 more Smart Citations

Which factors can influence post-operative renal function preservation after nephron-sparing surgery for kidney cancer: a critical review

Lascio

Sciarra

Giudice

et al. 2022

Cent european J Urol

View full text Add to dashboard Cite

Introduction The aim of this article was to compare different surgical approaches to perform nephron-sparing surgery (NSS) in terms of preservation of renal function. Material and methods We critically reviewed the literature from January 2000 to December 2020 including studies comparing different surgical techniques. Results A total of 51 studies met the inclusion criteria. Functional outcomes were evalutated in terms of percentual change of estimated glomerular filtration rate (eGFR) and impaired renal function (IRF) on scintigraphy. In cases with a mean age <60 years, the mean decrease in eGFR after NSS was 11.7% and that of IRF 10.0%, whereas higher changes were found in cases with a mean age ≥60 years. For open NSS, the mean eGFR and IRF changes were 15.3% and 21.1%, respectively; using the laparoscopic approach, the mean percentual eGFR and IRF changes were 13.9% and 11.1%, respectively; in robotic cases, the mean eGFR and IRF changes were 10.8% and 13.1%, respectively. In cases performed with global ischemia, the mean eGFR and IRF changes were 12.7% and 15.1%, respectively. Similar results were found distinguishing ischemia time ≤20 and >20 minutes, whereas using the off-clamp technique the mean decreases in eGFR and IRF were only 4.2% and 6%, respectively. Conclusions Patients’ age, tumor size, off-clamp technique, and robot-assisted approach were significant independent predictive factors able to influence renal function changes after NSS. A lower reduction of eGFR and IRF after NSS was reported in patients aged <60 years, submitted to a robot-assisted procedure, and using selective and cold ischemia <20 minutes or an off-clamp technique.

show abstract

“…The remaining 51 studies were included in this review ( Figure 1 ). Table 1 shows the characteristics of the included studies [ 8 – 58 ].…”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

“…Across the studies, RENAL score ranged from 5 to 9, with a mean value of 7.3. Four studies used the Padua score, which ranged from 6 to >10 ( Table 1 ) [ 34 , 39 , 50 , 58 ].…”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 3 more Smart Citations

Which factors can influence post-operative renal function preservation after nephron-sparing surgery for kidney cancer: a critical review

Lascio

Sciarra

Giudice

et al. 2022

Cent european J Urol

View full text Add to dashboard Cite

show abstract

Therapie des lokalisierten Nierenzellkarzinoms

Brinkmann,

Stief,

Marcon

2024

Urologie

View full text Add to dashboard Cite

Laparoscopic versus robotic abdominal and pelvic surgery: a systematic review of randomised controlled trials

2023

View full text Add to dashboard Cite

Background The current evidence is inconclusive on whether robotic or laparoscopic surgery is the optimal platform for minimally invasive surgery. Existing comparisons techniques focus on short-term outcomes only, while potentially being confounded by a lack of standardisation in robotic procedures. There is a pertinent need for an up-to-date comparison between minimally invasive surgical techniques. We aimed to systematically review randomised controlled trials comparing robotic and laparoscopic techniques in major surgery. Methods Embase, Medline and Cochrane Library were searched from their inception to 13th September 2022. Included studies were randomised controlled trials comparing robotic and laparoscopic techniques in abdominal and pelvic surgery. The study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Short-term, health-related quality of life, and long-term, outcomes were analysed. Results Forty-five studies, across thirteen procedures, involving 7364 patients were included. All of the studies reported non-significant differences in mortality between robotic and laparoscopic surgery. In majority of studies, there was no significant difference in complication rate (n = 31/35, 85.6%), length of postoperative stay (n = 27/32, 84.4%), and conversion rate (n = 15/18, 83.3%). Laparoscopic surgery was associated with shorter operative time (n = 16/31, 51.6%) and lower total cost (n = 11/13, 84.6%). Twenty three studies reported on quality of life outcomes; majority (n = 14/23, 60.9%) found no significant differences. Conclusion There were no significant differences between robotic surgery and laparoscopic surgery with regards to mortality and morbidity outcomes in the majority of studies. Robotic surgery was frequently associated with longer operative times and higher overall cost. Selected studies found potential benefits in post-operative recovery time, and patient-reported outcomes; however, these were not consistent across procedures and trials, with most studies being underpowered to detect differences in secondary outcomes. Future research should focus on assessing quality of life, and long-term outcomes to further elucidate where the robotic platform could lead to patient benefits, as the technology evolves.

show abstract

Robot-Assisted Laparoscopic Partial NephrectomyVsConventional Laparoscopic Partial Nephrectomy: Functional and Surgical Outcomes of a Prospective Single Surgeon Randomized Study

Cited by 20 publications

References 28 publications

Which factors can influence post-operative renal function preservation after nephron-sparing surgery for kidney cancer: a critical review

Which factors can influence post-operative renal function preservation after nephron-sparing surgery for kidney cancer: a critical review

Therapie des lokalisierten Nierenzellkarzinoms

Laparoscopic versus robotic abdominal and pelvic surgery: a systematic review of randomised controlled trials

Contact Info

Product

Resources

About