Construction is dangerous, making safety management essential. Robotics process automation (RPA) can improve construction project risk management. RPA is hindered by several factors. This study examined the primary technical, economic, legal, privacy, and resource obstacles to RPA adoption for tall building safety management. The pilot survey comprised 161 Malaysian tall building specialists, while the full questionnaire poll included 231 experts. EFA and SEM analyzed the data. Technology, economics, legislation, privacy, and resources prevented RPA from managing tall building safety. Theoretical and empirical breakthroughs in construction safety management and RPA deployment prompted this inquiry. This study illuminates the main obstacles to employing RPA for tall building safety management. The results show where to spend time and money to eliminate the obstacles. The study’s management implications may benefit construction safety managers, project managers, and company owners. The findings may help the building industry plan RPA safety management in tall projects and overcome hurdles. This study contributes to construction safety management and RPA deployment theory by identifying and analyzing the main barriers to using RPA for safety management in high-rise buildings. This research can help solve the problems preventing RPA from being used in construction project safety management.