Role of endothelial dysfunction in pathological cutaneous scarring

Roh, Mi Ryung

doi:10.1111/bjd.15974

Br J Dermatol

2017

DOI: 10.1111/bjd.15974

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Role of endothelial dysfunction in pathological cutaneous scarring

Mi Ryung Roh

Abstract: 6 Hampton T. Skin cancer's ranks rise: immunosuppression to blame. JAMA 2005; 294:1476-80. 7 Wei L, Allain DC, Bernhardt MN et al. Variants at the OCA2/HERC2 locus affect time to first cutaneous squamous cell carcinoma in solid organ transplant recipients collected using two different study designs. Br J Dermatol 2017; 177:1066-73. 8 Asgari MM, Toland AE, Arron ST. IRF4 polymorphism is associated with cutaneous squamous cell carcinoma in organ transplant recipients: a pigment-independent phenomenon. J Invest D… Show more

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2024

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Awareness of the impact of sex and gender in the disease risk and outcomes in hematology and medical oncology—a survey of Swiss clinicians

Darphin,

Moor,

da Silva

et al. 2024

Cancer Reports

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BackgroundAlthough male and female cancer patients are distinct in many ways, there is a limited understanding in the differences between male and female biology and differing pharmacokinetic responses to cancer drugs. In fact, sex and gender are currently not considered in most treatment decisions in the fields of oncology and hematology. The lack of knowledge about potential sex differences in both disciplines may lead to differences in treatment efficacy, toxicity, and the overall survival (OS) of patients.AimTo evaluate their awareness about sex and gender in clinical practice we surveyed Swiss hematologists and oncologists from September to November 2022.MethodsWe collected data about the clinical knowledge, experimental research, palliative care, quality of life, as well as the participant perception of the importance of sex and gender. We identified 767 eligible clinicians, of whom 150 completed the survey (20% response rate).ResultsWhile most participants agreed that sex and gender were relevant when treating patients, it became clear that fewer participants knew about sex and gender differences in treatment toxicity and survival, which in turn would affect the treatment of their patients. Most participants agreed that this topic should be integrated into continuing education and research.ConclusionOur findings indicate the need for more awareness and training on sex and gender in cancer research and clinical care among oncologists and hematologists. Ideally, by better educating medical students and health professionals, a demand is created for improving research policies, publications and therefore patient care.

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Awareness of the impact of sex and gender in the disease risk and outcomes in hematology and medical oncology—a survey of Swiss clinicians

Darphin,

Moor,

da Silva

et al. 2024

Cancer Reports

View full text Add to dashboard Cite

show abstract

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Role of endothelial dysfunction in pathological cutaneous scarring

Cited by 1 publication

References 9 publications

Awareness of the impact of sex and gender in the disease risk and outcomes in hematology and medical oncology—a survey of Swiss clinicians

Awareness of the impact of sex and gender in the disease risk and outcomes in hematology and medical oncology—a survey of Swiss clinicians

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