Role of pattern electroretinogram in assessment of retinal dysfunction in hypertensive patients

Zedan, Rasha; Farouk, Ayat Allah; Azmy, Radwa; Elhadidy, Reem; Attya, Eman

doi:10.1080/00207454.2021.1984237

Cited by 2 publications

(1 citation statement)

References 22 publications

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“…With the change of lifestyles, the incidence of diseases such as diabetes, glaucoma, and hypertension has increased significantly in the modern society [ 1 ]. These diseases may cause retinopathy, and severe cases may result in visual impairment and blindness.…”

Section: Introductionmentioning

confidence: 99%

Retinal Vessel Automatic Segmentation Using SegNet

Wang

Liang

et al. 2022

Computational and Mathematical Methods in Medicine

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Extracting retinal vessels accurately is very important for diagnosing some diseases such as diabetes retinopathy, hypertension, and cardiovascular. Clinically, experienced ophthalmologists diagnose these diseases through segmenting retinal vessels manually and analysing its structural feature, such as tortuosity and diameter. However, manual segmentation of retinal vessels is a time-consuming and laborious task with strong subjectivity. The automatic segmentation technology of retinal vessels can not only reduce the burden of ophthalmologists but also effectively solve the problem that is a lack of experienced ophthalmologists in remote areas. Therefore, the automatic segmentation technology of retinal vessels is of great significance for clinical auxiliary diagnosis and treatment of ophthalmic diseases. A method using SegNet is proposed in this paper to improve the accuracy of the retinal vessel segmentation. The performance of the retinal vessel segmentation model with SegNet is evaluated on the three public datasets (DRIVE, STARE, and HRF) and achieved accuracy of 0.9518, 0.9683, and 0.9653, sensitivity of 0.7580, 0.7747, and 0.7070, specificity of 0.9804, 0.9910, and 0.9885, F 1 score of 0.7992, 0.8369, and 0.7918, MCC of 0.7749, 0.8227, and 0.7643, and AUC of 0.9750, 0.9893, and 0.9740, respectively. The experimental results showed that the method proposed in this research presented better results than many classical methods studied and may be expected to have clinical application prospects.

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Section: Introductionmentioning

confidence: 99%

Retinal Vessel Automatic Segmentation Using SegNet

Wang

Liang

et al. 2022

Computational and Mathematical Methods in Medicine

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Neuroretinal Alterations in Schizophrenia and Bipolar Disorder: An Updated Meta-analysis

Sheehan,

Bannai,

Silverstein

et al. 2024

Schizophrenia Bulletin

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Schizophrenia (SZ) and bipolar disorder (BD) are characterized by major symptomatic, cognitive, and neuroanatomical changes. Recent studies have used optical coherence tomography (OCT) to investigate retinal changes in SZ and BD, but their unique and shared changes require further evaluation. Articles were identified using PubMed and Google Scholar. 39 studies met the inclusion criteria. Diagnostic groups were proband (SZ/BD combined), SZ, BD, and healthy control (HC) eyes. Meta-analyses utilized fixed and random effects models when appropriate, and publication bias was corrected using trim-and-fill analysis (“meta” package in R). Results are reported as standardized mean differences with 95% CIs. Data from 3145 patient eyes (1956 SZ, 1189 BD) and 3135 HC eyes were included. Studies identified thinning of the peripapillary retinal nerve fiber layer (pRNFL, overall and in 2 subregions), m-Retina (overall and all subregions), mGCL-IPL, mIPL, and mRPE in SZ patients. BD showed thinning of the pRNFL (overall and in each subregion), pGCC, and macular Retina (in 5 subregions), but no changes in thickness or volume for the total retina. Neither SZ nor BD patients demonstrated significant changes in the fovea, mRNFL, mGCL, mGCC, mINL, mOPL, mONL, or choroid thicknesses. Moderating effects of age, illness duration, and smoking on retinal structures were identified. This meta-analysis builds upon previous literature in this field by incorporating recent OCT studies and examining both peripapillary and macular retinal regions with respect to psychotic disorders. Overall, this meta-analysis demonstrated both peripapillary and macular structural retinal abnormalities in people with SZ or BD compared with HCs.

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Role of pattern electroretinogram in assessment of retinal dysfunction in hypertensive patients

Cited by 2 publications

References 22 publications

Retinal Vessel Automatic Segmentation Using SegNet

Retinal Vessel Automatic Segmentation Using SegNet

Neuroretinal Alterations in Schizophrenia and Bipolar Disorder: An Updated Meta-analysis

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