Role of PROPELLER diffusion-weighted imaging and apparent diffusion coefficient in the evaluation of pituitary adenomas

Is There Any Congruity Between Tumor Consistency in Pituitary Macroadenomas and Preoperative Diffusion Weighted Imaging and Apparent Diffusion Coefficient (ADC) Map?

“…We found that tumors with hard consistency display a slightly lower T2-weighted SI and ADC in different b values compared to intermediate and soft tumors, although it was not appreciably significant. Our results are consistent with Suzuki et al and Mahmoud et al findings that indicate DW and conventional MR imaging cannot provide sufficient information about predicting macroadenoma consistency (16,17). However, our findings were not in line with those of Pierallini et al and Mohamed et al (14,18).…”

“…Previous studies showed that GH-producing adenomas manifest significantly lower SI on T2-weighted images due to high protein concentration inside the secretory granules (10,17). We observed no significant difference in the conventional and DW MR imaging indices among pituitary adenomas with different secretory functions.…”

“…The correlation between tumor consistency and ADC values using periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER) DWI technique was evaluated by Mahmoud et al They concluded that ADC was not correlated with the consistency and hormone-secretion status of pituitary adenomas (17).…”

Evaluation of Diffusivity in the Anterior Lobe of the Pituitary Gland: 3D Turbo Field Echo with Diffusion-Sensitized Driven-Equilibrium Preparation

“…[1][2][3][4][5][6][7][8][9][10] However, it is difficult to evaluate skull base structures by the most common imaging technique used with echo-planar (EP)-DWI. Previous studies have revealed the efficacy of DWI for skull base tumors such as pituitary adenoma; however, they are mostly limited to macroadenomas large enough to calculate the ADC by using EP sequences.…”

Apparent diffusion coefficient and pituitary macroadenomas: pre-operative assessment of tumor atypia

“…Specifically, the ADC value is often correlated with tumor cellularity and tumor grade [14]. Furthermore, multiple prior studies have demonstrated the role of DWI in the evaluation of pituitary adenomas, ranging from preoperative assessment of tumor consistency to correlation of ADC with the proliferative marker MIB-1 [14][15][16][17][18].…”