Role of Streptococcus mutans in human dental decay.

Loesche, W. J.

doi:10.1128/mmbr.50.4.353-380.1986

Cited by 2,019 publications

(1,440 citation statements)

References 219 publications

(331 reference statements)

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“…Because these properties are not shared by all oral streptococci, cariogenic potential varies among species [3]. Several studies confirm a relationship between dental caries and mutans group streptococci, particularly Streptococcus mutans and S. sobrinus [4][5][6][7][8][9][10]. For this reason, it is important to accurately identify bacterial strains in accordance with current taxonomic standards [11][12][13].…”

Section: Introductionmentioning

confidence: 99%

Post-pH effect in oral streptococci

Castillo¹,

Rubiano²,

Gutiérrez³

et al. 2000

Clinical Microbiology and Infection

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Section: Introductionmentioning

confidence: 99%

Post-pH effect in oral streptococci

Castillo¹,

Rubiano²,

Gutiérrez³

et al. 2000

Clinical Microbiology and Infection

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“…Good oral hygiene and restriction in sugar consumption have been associated with dental caries reduction (1)(2)(3)(4)(5)(6)(7)(8)(9). The effect of oral hygiene is tnainly due to fluoridated toothpastes, which promote the remineralization of the enamel, while the consensus on the efficacy of plaque removal by toothbrushing is not unanimous (9)(10)(11)(12).…”

mentioning

confidence: 99%

“…The effect of oral hygiene is tnainly due to fluoridated toothpastes, which promote the remineralization of the enamel, while the consensus on the efficacy of plaque removal by toothbrushing is not unanimous (9)(10)(11)(12). Restriction in sugar consumption is another cariespreventive measure (5,13,14). However, some studies made in western countries report the lack of relationship between sugar restriction and caries reduction (see 13,15 for review).…”

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confidence: 99%

Oral hygiene, sucrose consumption and dental caries prevalence in adolescent systemic fluoride non‐users

Petti

Tarsitani

Panfili³

et al. 1997

Comm Dent Oral Epid

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“…increased numbers of cariogenic bacteria. Streptococcus mutans is generally considered to be a prime causative agent of dental caries [27]. However, its role in dental plaque formation is related not to the large number, but rather to the bacterial capability of rapid synthesis of adherent exopolysaccharides from dietary sucrose due to production of glucosyltransferases.…”

Section: As a Results Of Coaggregation Coadhesion Communication Andmentioning

confidence: 99%

Enzymes in therapy of biofilm‐related oral diseases

Pleszczyńska

Wiater

Bachanek

et al. 2016

Biotech and App Biochem

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Biofilm-related infections of the oral cavity, including dental caries and periodontitis, represent the most prevalent health problems. For years, the treatment thereof was largely based on antibacterial chemical agents. Recently, however, there has been growing interest in the application of more preventive and minimally invasive biotechnological methods. This review focuses on the potential applications of enzymes in the treatment and prevention of oral diseases. Dental plaque is a microbial community that develops on the tooth surface, embedded in a matrix of extracellular polymeric substances of bacterial and host origin. Both cariogenic microorganisms and the key components of oral biofilm matrix may be the targets of the enzymes. Oxidative salivary enzymes inhibit or limit the growth of oral pathogens, thereby supporting the natural host defense system; polysaccharide hydrolases (mutanases and dextranases) degrade important carbohydrate components of the biofilm matrix, whereas proteases disrupt bacterial adhesion to oral surfaces or affect cell-cell interactions. The efficiency of the enzymes in in vitro and in vivo studies, advantages and limitations, as well as future perspectives for improving the enzymatic strategy are discussed.

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Role of Streptococcus mutans in human dental decay.

Cited by 2,019 publications

References 219 publications

Post-pH effect in oral streptococci

Post-pH effect in oral streptococci

Oral hygiene, sucrose consumption and dental caries prevalence in adolescent systemic fluoride non‐users

Enzymes in therapy of biofilm‐related oral diseases

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