Role of the Matrix Effect in Analysis of Biological Objects Using Mass Spectrometry with Inductively Coupled Plasma

Elements in whole blood and urine were determined, and the influence of matrix spectral interference on the analysis results was evaluated in search of optimal measurement conditions on the quadrupole mass spectrometer with inductively coupled plasma Agilent 7700 that did not require correction when determining the varied elements in physical properties. The study showed that when using a quadrupole mass spectrometer, the detection limit of gallium in the studied biological fluids (both whole blood and urine) will be determined not by the background content of the element, but by the interfering effect of ions formed by the matrix components of the analyzed samples.

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Role of the Matrix Effect in Analysis of Biological Objects Using Mass Spectrometry with Inductively Coupled Plasma

Cited by 2 publications

References 14 publications

Rapid Determination of Calcium, Iron, and Zinc in Gluconate Oral Solutions by Solution Cathode Glow Discharge – Atomic Emission Spectroscopy (SCGD-AES)

Rapid Determination of Calcium, Iron, and Zinc in Gluconate Oral Solutions by Solution Cathode Glow Discharge – Atomic Emission Spectroscopy (SCGD-AES)

The role of the spectral matrix effect in the element analysis of biological fluids in ICP-MS

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