2022
DOI: 10.1016/j.jconrel.2022.04.026
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ROS-triggered nanoinducer based on dermatan sulfate enhances immunogenic cell death in melanoma

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Cited by 17 publications
(11 citation statements)
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“…Therefore, further efforts should be made to maximize the efficacy of ICI treatment. ICD targeting has been proved to be an effective way to prevent CM carcinogenesis ( Fu et al, 2022 ; Zhang et al, 2022 ). In our data, TIDE analysis between different groups was used to predict the effect of immunotherapy.…”
Section: Discussionmentioning
confidence: 99%
“…Therefore, further efforts should be made to maximize the efficacy of ICI treatment. ICD targeting has been proved to be an effective way to prevent CM carcinogenesis ( Fu et al, 2022 ; Zhang et al, 2022 ). In our data, TIDE analysis between different groups was used to predict the effect of immunotherapy.…”
Section: Discussionmentioning
confidence: 99%
“…The commonly induced stresses of ICD include tumor viruses and physiotherapy [ 26 ]. Various stresses can enhance ICD in melanoma, such as reactive oxygen species-triggered nanoinducer based on dermatan sulfate [ 27 ], zinc oxide-based multifunctional nanocomposites [ 28 ], and combined novel calreticulin-nanoparticles and focused ultrasonography [ 29 ]. In a mouse melanoma model, immune cells accumulate, and they are activated with a higher ICD [ 30 ].…”
Section: Introductionmentioning
confidence: 99%
“…For example, Li et al generated polymer micelles (named PPIR780-ZMS) containing IR780 dye and manganese zinc sulfide nanoparticles (ZMS), and revealed that PPIR780-ZMS could maximize ICD in melanoma and augment the infiltration of cytotoxic T cells (CD8+) and helper T cells (CD4+) [8]. Zhang et al synthesized a nanoinducer (named DOX/ADS NP) via the self-assembly of doxorubicin (DOX) and dermatan sulphate derivative (ADS) grafted by aromatic thioketal (ATK) [9]. This nano-inducer could enhance ICD and activate the immune response in melanoma, leading to shrinkage of tumor [9].…”
Section: Introductionmentioning
confidence: 99%
“…Zhang et al synthesized a nanoinducer (named DOX/ADS NP) via the self-assembly of doxorubicin (DOX) and dermatan sulphate derivative (ADS) grafted by aromatic thioketal (ATK) [9]. This nano-inducer could enhance ICD and activate the immune response in melanoma, leading to shrinkage of tumor [9].…”
Section: Introductionmentioning
confidence: 99%