2018
DOI: 10.15406/japlr.2018.07.00214
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RP- HPLC and TLC- densitometric methods for determination of oxfendazole in the presence of its alkali -induced degradation product

Abstract: Accurate, selective, and sensitive reversed phase high performance liquid chromatography (RP-HPLC) and thin-layer chromatography (TLC)-densitometry methods have been developed and validated for determination of oxfendazole in the presence of its alkaliinduced degradation product. The developed RP-HPLC method was based on the separation of the two components using 0.05M KH 2 PO 4 (adjusted to pH=5), methanol and actonitrile (50:30:20, by volume) as a mobile phase in isocratic elution mode on BDS Hypersil C 18 c… Show more

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