Abstract:Orlistat is an anti-obesity drug that inhibits the secretion of gastric and pancreatic lipases. Normally lipase breakdown triglyceride in the intestine as a result of metabolism. Despite the numerous advantages of this drug, researchers are facing problems with estimation by HPLC because limited methods are available; only United State Pharmacopoeia (USP) method is most reliable and effective. The present work aimed to develop an RP- HPLC method for determining orlistat in floating microcapsules. Considering t… Show more
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