Rs1800629 polymorphism in TNF-alpha is associated with the susceptibility and initial short-term glucocorticoids efficacy in myasthenia gravis patients

A case study: ADEM-like lesions as a first clinical event in highly active multiple sclerosis

“…19 in the 105 days following vaccination(Scola et al, 2023), but reports differ whether it can be associated with disease severity(Gupta et al, 2022;Pecoraro et al, 2023). The rs1800629 variant has also been implicated in higher risk for B-cell leukemia(Abdalhabib et al, 2022), lower response to corticosteroids in myasthenia gravis(Li et al, 2023), ine cacy of anti-TNF therapy(Padula et al, 2023), ischemic stroke susceptibility(Kamdee et al, 2021) and lower white matter integrity in schizophrenia(Kang et al, 2022). Variants of interest found in a neuroin ammation SNP panel.IgG binding capacity of FCGR2A(Omar et al, 2012), which is translated into differences in cytokine response(Stein et al, 2019).…”