RSV circulation during SARS-CoV-2 pandemic era: what happened in Italy

Matera, Luigi; Nenna, R; Frassanito, A; Conti, M G; Mattia, G Di; Petrarca, L; Mancino, E; Regina, D P La; Marseglia, G L; Licari, A; Leonardi, S; Manti, S; Nosetti, L; Pierangeli, A; Scagnolari, C; Jorgi, M Di; Solco, A; Moriano, C; Crinò, S; Bonci, E; Midulla, F

doi:10.1183/13993003.congress-2022.4138

Cited by 1 publication

(1 citation statement)

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“…In children, the higher number of naive and regulatory cells may help in avoiding the cytokine storm often associated with severe Covid-19 disease. Furthermore, recent studies report a considerable increase in the prevalence of respiratory viruses from 2022 to 2023 within the pediatric population [104], which suggests a significant change in viral activity. Respiratory syncytial virus (RSV) saw the greatest surge, which can be attributed to the lack of immune stimulation during the high pandemic period.…”

Section: Vaccines and The Role Of Boostersmentioning

confidence: 99%

The coevolution of Covid-19 and host immunity

Haque,

Pant

2024

Exploration of Medicine

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The dynamic of the virus-host interaction is subject to constant evolution, which makes it difficult to predict when the SARS-CoV-2 pandemic will become endemic. Vaccines in conjunction with efforts around masking and social distancing have reduced SARS-CoV-2 infection rates, however, there are still significant challenges to contend with before the pandemic shifts to endemic, such as the coronavirus acquiring mutations that allow the virus to dodge the immunity acquired by hosts. SARS-CoV-2 variants deploy convergent evolutionary mechanisms to sharpen their ability to impede the host’s innate immune response. The continued emergence of variants and sub-variants poses a significant hurdle to reaching endemicity. This underscores the importance of continued public health measures to control SARS-CoV-2 transmission and the need to develop better second-generation vaccines and effective treatments that would tackle current and future variants. We hypothesize that the hosts’ immunity to the virus is also evolving, which is likely to abet the process of reaching endemicity.

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Section: Vaccines and The Role Of Boostersmentioning

confidence: 99%