Rubella outbreak in Japan

Ujiie, Mugen; Nabae, Koji; Shobayashi, Tokuaki

doi:10.1016/s0140-6736(14)60712-1

Cited by 45 publications

(34 citation statements)

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“…These special programs may have contributed to the decrease in rubella cases. Because of this epidemic, the Ministry of Health, Labour and Welfare (MHW) decided to set a goal of rubella elimination by 2020 and to provide financial support to females of childbearing age and their partners for antibody testing from 2014 (10). MHW will recommend vaccination to those who are susceptible.…”

Section: Discussionmentioning

confidence: 99%

Epidemiological Characteristics of Rubella and Congenital Rubella Syndrome in the 2012–2013 Epidemics in Tokyo, Japan

et al. 2015

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Section: Discussionmentioning

confidence: 99%

Epidemiological Characteristics of Rubella and Congenital Rubella Syndrome in the 2012–2013 Epidemics in Tokyo, Japan

et al. 2015

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“…In 2011 the NNDSS reported 58 laboratory-confirmed cases of rubella in Australia, the highest number since 2002 [17]. In recent years, ongoing rubella outbreaks have been reported in Japan, China, and Vietnam, with associated CRS cases [23][24][25][26].…”

Section: Variables Amentioning

confidence: 99%

Surveillance for congenital rubella in Australia since 1993: Cases reported between 2004 and 2013

Khandaker

Zurynski

Jones

2014

Vaccine

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“…A rubella outbreak occurred in Japan in 2012 and 2013 (11), and 45 and 40 rubella cases, respectively, were reported in Himeji city during these outbreaks. Therefore, further studies should be performed to determine whether this outbreak affected the persistence of immunity after rubella vaccination.…”

Section: Discussionmentioning

confidence: 99%

Persistence of Immunity Acquired after a Single Dose of Rubella Vaccine in Japan

Okafuji¹,

Nakayama

2016

Jpn J Infect Dis

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SUMMARY:To date, Takahashi, Matsuura, and TO-336 strains of live-attenuated rubella vaccine have been used in Japan. Japan implemented a single-dose rubella vaccination program until 2006. However, few reports are available on the persistence of immunity after this vaccination program. We collected 276 serum samples from January 2009 to December 2011 at Okafuji Pediatric Clinic and assessed the immune status of these samples against rubella virus during 1-10 years after vaccination with a single dose of Takahashi rubella vaccine. Regional outbreak of rubella did not occur during 1999-2011. The collected serum samples were tested for antibodies against the rubella virus by performing a standard hemagglutination inhibition (HAI) test. Our results showed that all the tested serum samples contained antibodies against the rubella virus 10 years after the vaccination. Geometric mean titer of HAI antibodies was 1:180 and decreased to 1:68 at 10 years after the vaccination. The levels of HAI antibodies decreased logarithmically with time after the vaccination. In conclusion, vaccine-acquired immunity after vaccination with a single dose of live-attenuated Takahashi rubella vaccine was retained for at least 10 years when rubella was under regional control.

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Rubella outbreak in Japan

Cited by 45 publications

References 0 publications

Epidemiological Characteristics of Rubella and Congenital Rubella Syndrome in the 2012–2013 Epidemics in Tokyo, Japan

Epidemiological Characteristics of Rubella and Congenital Rubella Syndrome in the 2012–2013 Epidemics in Tokyo, Japan

Surveillance for congenital rubella in Australia since 1993: Cases reported between 2004 and 2013

Persistence of Immunity Acquired after a Single Dose of Rubella Vaccine in Japan

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Rubella outbreak in Japan

Cited by 45 publications

References 0 publications

Epidemiological Characteristics of Rubella and Congenital Rubella Syndrome in the 2012&ndash;2013 Epidemics in Tokyo, Japan

Epidemiological Characteristics of Rubella and Congenital Rubella Syndrome in the 2012&ndash;2013 Epidemics in Tokyo, Japan

Surveillance for congenital rubella in Australia since 1993: Cases reported between 2004 and 2013

Persistence of Immunity Acquired after a Single Dose of Rubella Vaccine in Japan

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Epidemiological Characteristics of Rubella and Congenital Rubella Syndrome in the 2012–2013 Epidemics in Tokyo, Japan

Epidemiological Characteristics of Rubella and Congenital Rubella Syndrome in the 2012–2013 Epidemics in Tokyo, Japan