Rural and urban differences in prenatal exposure to essential and toxic elements

Cottrell, Jesse; Thomas, D’Andrea S; Mitchell, Brenda; Childress, Jason E; Dawley, Diane; Harbrecht, Lawrence E; Jude, David C.; Valentovic, Monica

doi:10.1080/15287394.2018.1547890

Cited by 11 publications

(5 citation statements)

References 35 publications

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“…They found significant differences between rural and urban samples in which the Cu content was much higher in urban samples than in rural samples. However, the authors did not find any significant differences between the groups for Cd and Zn [54].…”

Section: Discussionmentioning

confidence: 79%

“…The use of umbilical cord blood and the mother's blood, which is easily available, is appropriate for the assessment of foetal exposure to Cu, Zn and Cd. Cottrell et al (2018) researched inorganic elements in umbilical cord blood in rural and urban areas in the USA. They found significant differences between rural and urban samples in which the Cu content was much higher in urban samples than in rural samples.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Relationship between concentrations of elements and geographic location in Poland

Tomska

Kosik-Bogacka

Łanocha-Arendarczyk

et al. 2021

Ann Agric Environ Med.

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Introduction.Interactions occur between concentrations of metals in the human body and the environment in various geographic locations, which can be of importance for both the proper development and the course of pregnancy. Objective. The aim of the study was to assess the concentrations of Zn, Cu and Cd and Zn:Cu and Zn:Cd molar ratios in the placenta, umbilical cord and in the foetal membrane, and to examine the relationship between concentrations of these elements and the place of residence. Materials and method. The research material was obtained from 99 healthy women from north-western and central Poland. Data for the study were collected from the medical history and documents of admission to the ward and documents confirming the birth of the newborn. Concentrations of zinc (Zn), copper (Cu) and cadmium (Cd) were determined using the ICP-AES method (spectrophotometry of atomic absorption) in inductively coupled argon plasma. Results. The average concentration of Zn, Cu and Cd in afterbirths was ~ 0.01 mg/kg of dry weight (dw). In central Poland, the results revealed a significant increase in zinc in the membrane (OR=1.098, p=0.002), cadmium in the placenta (OR=1.324, p=0.006), Zn:Cu in the membrane (OR=1.012, p<0.001). In north-western Poland, an increase in copper in the membrane (OR=1.239, p=0.025) was revealed. Conclusions. The use biological materials, such as the placenta, foetal membrane and umbilical cord to assess exposure to heavy metals and necessary elements is justified.

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Section: Discussionmentioning

confidence: 79%

Section: Discussionmentioning

confidence: 99%

Relationship between concentrations of elements and geographic location in Poland

Tomska

Kosik-Bogacka

Łanocha-Arendarczyk

et al. 2021

Ann Agric Environ Med.

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“…This may be caused by different economic levels and eating habits between urban and rural areas. However, in the study of differences between rural and urban elements, there was no difference in the population distribution of Mg [21]. Magnesium deficiency also leads to an increase in glucose.…”

Section: Discussionmentioning

confidence: 88%

Magnesium Nutritional Status, Risk Factors, and the Associations with Glucose Parameters of Childbearing Women in the China Adult Chronic Disease and Nutrition Surveillance (2015)

et al. 2022

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Magnesium is an essential element and participates in many metabolic pathways. Inadequate magnesium levels may lead to various health problems such as type 2 diabetes (T2DM), hypertension, and cancer. But the role of Mg in childbearing women of China is still a relatively narrow researched field. We aimed to assess the Mg nutritional status, explore the risk factors of Mg deficiency, and the associations between Mg and glucose parameters among childbearing women in a nationally representative sample. A total of 1895 18–44 y childbearing women were recruited from the China Adult Chronic Disease and Nutrition Surveillance (2015). Multivariate logistic regression was used to explore the risk factors for Mg deficiency and estimate the odds ratios (ORs) and 95% confidence intervals (95% CIs) for the risk of hyperglycemia. The mean value of Mg was 0.87 mmol/L and the prevalence of deficiency was 4.69%. The risk factors of Mg deficiency (Mg < 0.75 mmol/L) was city-type of rural (p = 0.045), while calcium (p = 0.001), LDL-C (p = 0.024), age group of 26–35 y (p = 0.016), 36–44 y (p = 0.006), and CNNM2 rs3740393 genotypes of GC (p = 0.027) were protective factors. It was also found that magnesium deficiency induces an increase in plasma glucose (p = 0.001). Compared with the reference range, Mg < 0.75 mmol/L would have a 6.53 fold risk for T2DM, a 5.31 fold risk for glucose-hyperglycemia, and a 9.60 fold risk for HbA1c-hyperglycemia. Consistently, there was a negative association between plasma Mg and blood glucose parameters in the dose–response study. More attention should be paid to the nutritional status of magnesium and the impact of magnesium deficiency on human health.

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“…Environmental exposure to toxins is present in rural and urban facilities, which leads to toxic concentrations of these compounds in different regions of the CNS. Furthermore, they may have a neurobiological effect even during prenatal in utero stages [70], leading to future developmental consequences. For example, exposure to lead and cadmium in with learning disabilities in a rural population is related to differences in IQ performance, demonstrating that higher lead concentrations measured from hair are inversely correlated with intelligence and brain functioning [71].…”

Section: Eeg Environmental and Social Risk Factorsmentioning

confidence: 99%

Neuropsychology and Electroencephalography in Rural Children at Neurodevelopmental Risk: A Scoping Review

Galindo-Aldana,

Torres-González

2023

Pediatric Reports

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Children from rural areas face numerous possibilities of neurodevelopmental conditions that may compromise their well-being and optimal development. Neuropsychology and electroencephalography (EEG) have shown strong agreement in detecting correlations between these two variables and suggest an association with specific environmental and social risk factors. The present scoping review aims to describe studies reporting associations between EEG features and cognitive impairment in children from rural or vulnerable environments and describe the main risk factors influencing EEG abnormalities in these children. The method for this purpose was based on a string-based review from PubMed, EBSCOhost, and Web of Science, following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA). Qualitative and quantitative analyses were conducted from the outcomes that complied with the selected criteria. In total, 2280 records were identified; however, only 26 were eligible: 15 for qualitative and 11 for quantitative analysis. The findings highlight the significant literature on EEG and its relationship with cognitive impairment from studies in children with epilepsy and malnutrition. In general, there is evidence for the advantages of implementing EEG diagnosis and research techniques in children living under risk conditions. Specific associations between particular EEG features and cognitive impairment are described in the reviewed literature in children. Further research is needed to better describe and integrate the state of the art regarding EEG feature extraction.

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Rural and urban differences in prenatal exposure to essential and toxic elements

Cited by 11 publications

References 35 publications

Relationship between concentrations of elements and geographic location in Poland

Relationship between concentrations of elements and geographic location in Poland

Magnesium Nutritional Status, Risk Factors, and the Associations with Glucose Parameters of Childbearing Women in the China Adult Chronic Disease and Nutrition Surveillance (2015)

Neuropsychology and Electroencephalography in Rural Children at Neurodevelopmental Risk: A Scoping Review

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