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Cited by 2 publications
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“…As stated above, ruxolitinib doses and timing of administration greatly influence the immune state, the subsequent pathogen clearance and survival [84]. Besides, a withdrawal syndrome is described when patients cease ruxolitinib treatment, which is termed "ruxolitinib discontinuation syndrome" and can lead to a cytokine storm that could be highly detrimental in a context of sepsis [89].…”
Section: Modulators Of the Jak-stat Pathways And Applicability In Sepsismentioning
confidence: 99%
“…As stated above, ruxolitinib doses and timing of administration greatly influence the immune state, the subsequent pathogen clearance and survival [84]. Besides, a withdrawal syndrome is described when patients cease ruxolitinib treatment, which is termed "ruxolitinib discontinuation syndrome" and can lead to a cytokine storm that could be highly detrimental in a context of sepsis [89].…”
Section: Modulators Of the Jak-stat Pathways And Applicability In Sepsismentioning
confidence: 99%
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