S‐Methyl Isothiourea Sulfate

Abstract

S‐methyl isothiourea sulfate S‐methyl isothiourea sulfate

Reduction of Pyrimidine Derivatives by LiAlH4

“…Thiourea was treated with dimethyl sulfate to form S-methylisothiouronium sulfate (5). 2 The synthesis of ethyl 3-dimethylamino-2-formylacrylate (7) involved the reaction of a Vilsmeier reagent, which was derived from N,N-dimethylformamide and phosphorus oxychloride, with potassium ethyl malonate (6). 3,4 Reaction of 5 with 7 afforded ethyl 2-(methylthio)pyrimidine-5-carboxylate (1).…”

Synthesis and antimicrobial activity of certain new 1,2,4-triazolo[1,5-a]pyrimidine derivatives

“…The following starting materials and reagents were prepared according to reported methods: Ethyl benzoate (Furniss et al, 1991); Benzoic acid hydrazide (Prager et al, 1944); S-Methylisothiourea sulfate (Shildneck et al, 1921); Benzoylaminoguanidine (Hoggarth E., 1950); 3-Amino-5-phenyl-2H-1,2,4-triazole (Hoggarth E., 1950); 5-Methyl-2-phenyl-1,2,4-triazolo[1,5-a]pyrimidin-7-ol (Lipinski C. A., 1983); Different phenacyl bromides (Shevehuk et al, 1963). Other chemicals and reagents were of reagent grades.…”