S160 The effect of shift work on serial peak expiratory flow measurements used to diagnose occupational asthma

Moore, Vicky; Jaakkola, Maritta S.; Burge, Cedd; Pantin, C. F. A.; Robertson, Alastair; Burge, P. S.

doi:10.1136/thx.2010.150953.11

Cited by 19 publications

(35 citation statements)

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“…3) The sensitivity and specificity of serial peak flow measurements is high in the diagnosis of work-related asthma (***) [48].…”

Section: Strength Of Evidence and Grading Of Recommendationmentioning

confidence: 99%

“…The evidence for serial measurements of peak expiratory flow (PEF) is taken from an evidence-based review [48] and is compatible with the AHRQ meta-analysis.…”

Section: Commentsmentioning

confidence: 99%

“…This can only be done when the patient is still exposed to the suspected cause of their symptoms, so it needs to be the first confirmatory test. Serial measurement of PEF on days at and away from work is the best validated method and is recommended in all guidelines [48]. Attention to detail is important.…”

Section: Commentsmentioning

confidence: 99%

See 2 more Smart Citations

Guidelines for the management of work-related asthma

Baur

Sigsgaard²,

Aasen³

et al. 2012

Eur Respir J

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183

182

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Work-related asthma, which includes occupational asthma and work-aggravated asthma, has become one of the most prevalent occupational lung diseases. These guidelines aim to upgrade occupational health standards, contribute importantly to transnational legal harmonisation and reduce the high socio-economic burden caused by this disorder.A systematic literature search related to five key questions was performed: diagnostics; risk factors; outcome of management options; medical screening and surveillance; controlling exposure for primary prevention. Each of the 1,329 retrieved papers was reviewed by two experts, followed by Scottish Intercollegiate Guidelines Network grading, and formulation of statements graded according to the Royal College of General Practitioners' three-star system.Recommendations were made on the basis of the evidence-based statements, which comprise the following major evidence-based strategic points. 1) A comprehensive diagnostic approach considering the individual specific aspects is recommended. 2) Early recognition and diagnosis is necessary for timely and appropriate preventative measures. 3) A stratified medical screening strategy and surveillance programme should be applied to at-risk workers. 4) Whenever possible, removing exposure to the causative agent should be achieved, as it leads to the best health outcome. If this is not possible, reduction is the second best option, whereas respirators are of limited value. 5) Exposure elimination should be the preferred primary prevention approach.

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“…3) The sensitivity and specificity of serial peak flow measurements is high in the diagnosis of work-related asthma (***) [48].…”

Section: Strength Of Evidence and Grading Of Recommendationmentioning

confidence: 99%

“…The evidence for serial measurements of peak expiratory flow (PEF) is taken from an evidence-based review [48] and is compatible with the AHRQ meta-analysis.…”

Section: Commentsmentioning

confidence: 99%

See 1 more Smart Citation

Guidelines for the management of work-related asthma

Baur

Sigsgaard²,

Aasen³

et al. 2012

Eur Respir J

Self Cite

183

182

View full text Add to dashboard Cite

show abstract

“…5). When serial PEFs are of good quality, the mean pooled sensitivity for the diagnosis of occupational asthma is 82% and specificity is 89% [13]. FEV1 is the main measure used in specialised testing, such as specific inhalation challenge tests for the diagnosis of occupational asthma.…”

Section: Spirometry In the Workplacementioning

confidence: 99%

Spirometry: step by step

Moore

2012

Breathe

138

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N To give an overview of what spirometry is, how to perform it and how to interpret it. N To discuss the quality criteria to produce acceptable and reproducible results. N To discuss the use of spirometry in the workplace. SummarySpirometry is easy to perform once trained and can be performed anywhere. It is useful for detecting early change and disease progression. Quality is important to ensure useful and reproducible results, otherwise results may be incorrectly interpreted. Training from a reputable centre should be undertaken to ensure the measures are understood as well as how to get the best results out of the patient.

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“…The diagnosis of asthma was based on the history of asthmatic symptoms and positive metacholine challenge test [11]. The workrelatedness of asthma was evaluated by serial peak expiratory flow rate (PEFR) measurements according to the actual recommendations [12,13]. The diagnosis of OA (sensitizer-induced OA) was established by finding of significant changes of the PEFR values registered in the periods at and away from work [14].…”

Section: Diagnostic Work-upmentioning

confidence: 99%