S2841 Autoimmune Hepatitis: Possible Relation to the Pfizer-BioNTech COVID-19 Vaccine?

Ventura, Frank L; John, Jaison S.; Al-Saadi, Yamam I.; Stevenson, Heather L.; Khan, Kashif

doi:10.14309/01.ajg.0000784896.23722.94

“…Moreover, several case reports exist that speculate an association between the Pfizer-BioNTech mRNA vaccine and the development of acute hepatitis. For example, Ventura et al [ 14 ] describe the case of a 38-year-old woman who presented with acute hepatitis 2 wk after receiving the second dose of the Pfizer vaccine. The patient’s liver enzymes, as with ours, were very elevated (ALT 3769 U/L and AST 1572 U/L) and recovered with the administration of corticosteroids.…”

Section: Discussionmentioning

confidence: 99%

Acute hepatitis of unknown etiology in an adult female: A case report

Dass,

Pacia,

Hamidi

2023

World J Clin Cases

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In recent years, because of the growing desire to improve the noninvasiveness and safety of tumor treatments, sonodynamic therapy has gradually become a popular research topic. However, due to the complexity of the therapeutic process, the relevant mechanisms have not yet been fully elucidated. One of the widely accepted possibilities involves the effect of reactive oxygen species. In this review, the mechanism of reactive oxygen species production by sonodynamic therapy (SDT) and ways to enhance the sonodynamic production of reactive oxygen species are reviewed. Then, the clinical application and limitations of SDT are discussed. In conclusion, current research on sonodynamic therapy should focus on the development of sonosensitizers that efficiently produce active oxygen, exhibit biological safety, and promote the clinical transformation of sonodynamic therapy.

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Tozinameran

2021

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Acute hepatitis of unknown etiology in an adult female: A case report

Dass,

Pacia,

Hamidi

2023

World J Clin Cases

0

View full text Add to dashboard Cite

In recent years, because of the growing desire to improve the noninvasiveness and safety of tumor treatments, sonodynamic therapy has gradually become a popular research topic. However, due to the complexity of the therapeutic process, the relevant mechanisms have not yet been fully elucidated. One of the widely accepted possibilities involves the effect of reactive oxygen species. In this review, the mechanism of reactive oxygen species production by sonodynamic therapy (SDT) and ways to enhance the sonodynamic production of reactive oxygen species are reviewed. Then, the clinical application and limitations of SDT are discussed. In conclusion, current research on sonodynamic therapy should focus on the development of sonosensitizers that efficiently produce active oxygen, exhibit biological safety, and promote the clinical transformation of sonodynamic therapy.

show abstract

S2841 Autoimmune Hepatitis: Possible Relation to the Pfizer-BioNTech COVID-19 Vaccine?

Cited by 3 publications

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Acute hepatitis of unknown etiology in an adult female: A case report

Acute hepatitis of unknown etiology in an adult female: A case report

Tozinameran

Acute hepatitis of unknown etiology in an adult female: A case report

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