S643 Gastric Polyps: Examining Adherence to Polypectomy Guidelines and the Role of Demographic and Clinical Data in Endoscopic Management

Abstract

Introduction: Helicobacter pylori (H. pylori) is a widely prevalent infection considered a significant public health challenge. It is a major cause of gastroduodenal disorders, including gastric cancer. Thus prompt diagnosis and treatment are required for eradication. Nigeria has the highest worldwide H. pylori prevalence. Aims: To determine the spectrum of endoscopic findings in patients with H.pylori infectionat a tertiary care academic medical center. Methods: This retrospective hospital-based study was conducted between April 2018 and April 2022 among patients aged $18 years with dyspepsia. H. pylori was evaluated using non-invasive tests (urea breath test and fecal antigen test). Patients who tested positive for H. pylori and were further assessed with upper gastrointestinal endoscopy were included in the study. Demographics, clinical data, and endoscopic findings were extracted for analysis. A descriptive analysis of data obtained was carried out using SPSS version 20. Results: One hundred and twenty-nine (129) patients tested positive for H. pylori infection out of the two hundred and eighty dyspeptic patients evaluated during the period under study. However, only fifty-two (52) out of 129 dyspepticpatients who tested positive for H.pylori were evaluated with upper gastrointestinal endoscopy and thus met the inclusion criteria. Thirty-one (59.62%) were males, and 21 (40.38%) were females. The mean age was 45.65 years, with a range of 21-76 years. (Figure ) Upper gastrointestinal endoscopy among the patients revealed predominantly gastritis 37 (71.15%), with gastritis involving the corpus and antral area being the most typical form. Others were gastro-duodenitis in 4 (7.7%), esophagitis in 4 (7.7%), gastric ulcer in 3 (5.8%), and duodenal ulcer in 2 (3.8%), and gastric tumor in 2 (3.8%). Conclusion: Our study revealed that gastritis was the predominant endoscopic finding in patients with H. pylori infection. This finding is particularly significant because of the risk of progression of chronic gastritis in some of these patients to intestinal metaplasia, dysplasia, and gastric cancer. Hence, endoscopy with gastric biopsy should be obtained in patients with gastric erythema for early diagnosis and treatment.[0641] Figure 1. Socio demographics and spectrum of the endoscopic images A-Sex distribution of the study population. B-Age distribution of the study population. C-Endoscopic findings of the study population. D-Endoscopic image showing a widespread patchy redness involving the corpus and the antrum. E-Endoscopic image of fungating gastric mass involving the body and the antrum. F-Endoscopic image of a Forrest III gastric ulcer located on the lesser curvature.