Saddle nose deformity, palatal perforation and truncus arteriosus in a patient with Crohn’s disease

Oğhan, Fatih; Pekkan, Gürel; Özveren, Olcay

doi:10.1016/j.jcms.2011.01.010

Cited by 5 publications

(2 citation statements)

References 23 publications

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“…Histopathologic examination of nasal biopsies may demonstrate non--specific chronic inflammation [15]. It also showed non--caseating granulomas in the majority of patients, as in our case [10][11][12][13]. Pharyngeal or laryngeal involvement, pansinusitis, peritonsillitis and oral ulcerations were also described in some of these patients [12].…”

Section: Discussionmentioning

confidence: 75%

“…In our patient, nasal obstruction and recurrent epistaxis were the main symptoms. Chronic atrophic or scabby rhinitis, oedema, ulcerations and polyposis of nasal mucosa, perforation of nasal septum, lysis and necrosis of the turbinates, saddle nose deformity, stenosis of the nasal fossae and empty nose syndrome were the most common endoscopic findings in these patients [10][11][12][13]. Nasal involvement with septum perforation, excoriation of the left nasal septum and abundant mucus revealed CD in only one patient [14].…”

Section: Discussionmentioning

confidence: 99%

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A Rare Manifestation of Crohn's Disease: Sinonasal Granulomatosis. Report of a Case and Review of Literature

Baïli

Rachdi

Daoud

et al. 2014

European Journal of Case Reports in Internal Medicine

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Abstract:Crohn's disease is a granulomatous inflammatory bowel disease. Its pathologic findings include non--contiguous chronic inflammation and non--caseating granulomas, sometimes with extra--intestinal localizations. Sinonasal manifestations of Crohn's disease are quite rare and only a few cases have been reported up to date in the worldwide literature. They are characterized by chronic mucosal inflammation, obstruction, bleeding and occasionally septal perforation. We report a case of sinonasal granulomatosis revealing Crohn's disease in a 22--year--old woman and go over the available literature on sinonasal involvement in Crohn's disease.

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