Safety analysis and risk management of autologous fat grafting in facial anti-aging

Abstract

Ageing makes facial tissue aging unavoidable, which is mainly manifested as tissue volume reduction and contour change, and autologous fat grafting can better meet the clinical application of facial anti-aging. In the article, a total of 80 patients with poor facial contour or facial aging from May 2022 to July 2023 in NanChang HanYa Aesthetic Hospital were selected. The lower abdomen or inner and outer thigh fat was extracted by swelling solution. The acquired fat was filtered, purified, and cleaned. Then, the autologous fat particles were injected above the face using a blunt-ended injection needle. The risk factors were analyzed by using the multivariate regression model. The effective rate of treatment effect based on autologous fat transplantation reached 92.50%. The MMP-1 level of the patients in the observation group was reduced from 125.34±12.45 ng/ml before the operation to 102.41±7.32 ng/ml after the operation. The facial skin texture of the patients was significantly improved. Patients with autologous fat grafting had a low complication rate of only 10%, and they were satisfied with the results of facial anti-aging treatment at 96%. Under clinical conditions, the incidence of EAD risk was higher in mixed steatosis (OR=4.715, 95% CI 1.413-8.792). Facial volume restoration and improvement of facial aging can be effectively achieved by autologous fat grafting, and patients were satisfied with the facial anti-aging results. Still, the clinical risks caused by autologous fat degeneration also need to be noted.