Safety and Efficacy Studies of Vertebroplasty with Dual Injections for the Treatment of Osteoporotic Vertebral Compression Fractures: Preliminary Report

Cao, Pijian; Hao, Weimin; Zhang, Lu; Liu, Xunwei; Li, Min

doi:10.1016/j.acra.2019.09.023

Cited by 4 publications

(3 citation statements)

References 27 publications

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“…The possible causes include the presence of an IVC sign, a viscosity of injected cement, injection volume and velocity, and the morphology of the fractured vertebral body [ 27 ]. In our study, cement (PMMA) leakage occurred in 1 patient, with a rate of 3.7% (1 out of 27), which is lower than the rate reported in previous studies for new OVCFs (10%) [ 28 ]. Therefore, we speculated that leakage and obsolete OVCFs are not significantly related.…”

Section: Discussioncontrasting

confidence: 79%

Comparison between percutaneous short-segment fixation and percutaneous vertebroplasty in treating Kummell’s disease: A minimum 2-year follow-up retrospective study

Shen,

Tang,

Yin

et al. 2024

BMR

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BACKGROUND: Percutaneous kyphoplasty (PKP) or percutaneous short-segment fixation (PSSF) is often used to treat Kummell’s disease. However, it is not clear which treatment is better for patients. OBJECTIVE: To retrospectively compare the clinical efficacy of PVP and PSSF for the treatment of Kummell’s disease. METHOD: 60 patients were involved in this research and the period of follow-up was at least 2 years. 27 of them were treated with PVP (Group I) and the rest who received PSSF (Group II). The visual analog scale (VAS) and radiographic indexes of each participant had been measured preoperatively as well as 1 week, 3 months, and 2 years postoperatively. Additionally, the Oswestry Disability Index (ODI) scores were assessed at the last time point. RESULTS: Comparing the two groups, no statistical significance was found among all parameters preoperatively. The time of operations and blood loss is less in Group I. At each time point after operation, the imaging indices in Group II are lower (P< 0.05). One week after treatments, the VAS scores are lower in Group I, and similarly, 3 months are the same (P< 0.05), while VAS are similar at the last time point. In the aspect of ODI scores, they are lower in Group II during long-term follow-up. CONCLUSION: For the treatment of Kummell’s disease, both PVP and PSSF have been found to be effective. PVP can provide rapid pain relief with a shorter operation time. However, in cases with severe kyphosis deformity, PSSF should be given priority.

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Section: Discussioncontrasting

confidence: 79%

Comparison between percutaneous short-segment fixation and percutaneous vertebroplasty in treating Kummell’s disease: A minimum 2-year follow-up retrospective study

Shen,

Tang,

Yin

et al. 2024

BMR

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“…All the patients operated successfully, and no complication including never injury and pulmonary embolism has happened (8). The average operation time is (27.7±6.5) minutes, the average injection volume of PMMA cement is (4.40±1.74)ml, and the average amount of bleeding is (5.61±2.11)ml.…”

Section: General Situationmentioning

confidence: 90%

The change of sagital balance after PKP for patients with osteoporotic vertebral compression

Li¹,

Zhang²,

Ren³

et al. 2020

Preprint

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Purpose To detect the postoperative change in total spinal alignment in 0VCF patients after PKP. Methods A total of 130 patients with vertebral compression fracture was involved in this study. The entire spine radiographs of every patients were taken pre and postoperatively. The parameters including vertebral body height, pelvic incidence (PI), sacral slope (SS), pelvic tilt (PT), lumbar lordosis (LL), sagittal vertical axis (SVA), and spinosacral angle (SSA). All the parameters were compared before and after PKP. Results In the patients, the VAS score was decreased from 8.26±1.12 preoperative to 2.70±0.90 postoperative. And SVA decreased from 6.82±3.30 cm to 4.07±2.77cm. The change in sagittal balance is related to the recovery of vertebral body height. Conclusion PKP plays a role not only in improving the vertebral body height but also in rebuilding sagittal imbalance in the treatment of vertebral compression fracture.

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“…With the development of spinal minimally invasive surgery, percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP) have become the gold standard for the treatment of OVCF. They both can reduce pain immediately, improve functional activities and cut down other complications [1,2]. However, post-operative OVCF patients with residual pain were often found clinically and in related reports.…”

Section: Introductionmentioning

confidence: 99%

Factors and Strategies for Post-Vertebroplasty Residual Pain from Thoracolumbar Osteoporotic Vertebral Compression Fractures (OVCF): a systematic review.

Tang

Liu

et al. 2021

Preprint

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Purpose Insignificant pain relief (IPR) in short period after vertebroplasty is common, which often disturb doctors and affect patients Therefore, we reviewed systematically relative articles and attempted to get meaningful evidence on factors and strategies for IPR.Methods PubMed, Web of Science, Embase, CNKI, WanFang, and VIP were searched for literatures treating the osteoporotic vertebral compression fractures (OVCFs) with vertebroplasty and assessing the clinical efficacy.Results 817 references were electronically retrieved, 81 full-text papers were screened and 41 studies were included. Twenty-two trials presented factors on IPR, mainly including bone cement related, operation related and patient-related factors. Nineteen studies showed strategies on residual pain, including improving osteoporosis, reforming surgical operation and add other therapies. 16 prospective, 20 retrospective and 5 meta-analyses consisted the systematic review. The date from included studies point to different results, with less risk of bias, were needed to clarify the factors and strategies for residual pain.Conclusions Bone cement distribution and operation error are highly related to the post-vertebroplasty residual pain. Many therapeutic methods could improve pain and rehabilitate function but lacking more high-level evidence due to the insufficient trails.

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Safety and Efficacy Studies of Vertebroplasty with Dual Injections for the Treatment of Osteoporotic Vertebral Compression Fractures: Preliminary Report

Cited by 4 publications

References 27 publications

Comparison between percutaneous short-segment fixation and percutaneous vertebroplasty in treating Kummell’s disease: A minimum 2-year follow-up retrospective study

Comparison between percutaneous short-segment fixation and percutaneous vertebroplasty in treating Kummell’s disease: A minimum 2-year follow-up retrospective study

The change of sagital balance after PKP for patients with osteoporotic vertebral compression

Factors and Strategies for Post-Vertebroplasty Residual Pain from Thoracolumbar Osteoporotic Vertebral Compression Fractures (OVCF): a systematic review.

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